Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MBTPS2
  • Mouse genes Mbtps2
  • Rat genes Mbtps2
  • Zfish genes mbtps2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mbtps2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004222	metalloendopeptidase activity	MBTPS2	EXP		Human	PMID:11163209
Molecular Function	GO:0004222	metalloendopeptidase activity	MBTPS2	IDA		Human	PMID:11163209
Cellular Component	GO:0005737	cytoplasm	MBTPS2	IDA		Human	PMID:19361614
Biological Process	GO:0070977	bone maturation	MBTPS2	IMP		Human	PMID:27380894
Biological Process	GO:0051216	cartilage development	mbtps2	IMP	ZFIN:ZDB-MRPHLNO-110422-4	Zfish	PMID:14612568
Biological Process	GO:0006629	lipid metabolic process	mbtps2	IMP	ZFIN:ZDB-MRPHLNO-110422-4	Zfish	PMID:14612568
Biological Process	GO:0031293	membrane protein intracellular domain proteolysis	MBTPS2	IGI	UniProtKB:O54862	Human	PMID:11163209
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	MBTPS2	IGI	UniProtKB:O54862	Human	PMID:11163209
Biological Process	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	MBTPS2	IGI	UniProtKB:O54862	Human	PMID:11163209
Biological Process	GO:0051604	protein maturation	MBTPS2	EXP		Human	PMID:11163209
Biological Process	GO:0051604	protein maturation	MBTPS2	IDA		Human	PMID:11163209

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern