Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAP4K3
  • Mouse genes Map4k3
  • Rat genes Map4k3
  • Zfish genes map4k3a,map4k3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Map4k3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	MAP4K3	IDA		Human	PMID:9275185
Molecular Function	GO:0005515	protein binding	MAP4K3	IPI	UniProtKB:P62993	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	MAP4K3	IPI	UniProtKB:P62993	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	MAP4K3	IPI	UniProtKB:Q02111	Human	PMID:21983831
Molecular Function	GO:0005515	protein binding	MAP4K3	IPI	UniProtKB:Q04759	Human	PMID:21983831
Molecular Function	GO:0005515	protein binding	MAP4K3	IPI	UniProtKB:Q13094	Human	PMID:21983831
Molecular Function	GO:0005515	protein binding	Map4k3	IPI	UniProtKB:Q02111|UniProtKB:Q13094	Mouse	MGI:MGI:5295782|PMID:21983831
Molecular Function	GO:0004674	protein serine/threonine kinase activity	MAP4K3	IDA		Human	PMID:9275185
Molecular Function	GO:0017124	SH3 domain binding	Map4k3	IPI	RGD:620276	Rat	PMID:11384986|RGD:727317
Biological Process	GO:0035556	intracellular signal transduction	MAP4K3	IDA		Human	PMID:9275185
Biological Process	GO:0006468	protein phosphorylation	MAP4K3	IDA		Human	PMID:9275185
Biological Process	GO:0034612	response to tumor necrosis factor	MAP4K3	IDA		Human	PMID:9275185
Biological Process	GO:0009411	response to UV	MAP4K3	IDA		Human	PMID:9275185

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern