Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LY86
  • Mouse genes Ly86
  • Rat genes Ly86
  • Zfish genes ly86
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ly86

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LY86	IPI	UniProtKB:Q99467	Human	PMID:21857663
Molecular Function	GO:0005515	protein binding	LY86	IPI	UniProtKB:P57678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ly86	IPI	UniProtKB:Q62192	Mouse	MGI:MGI:5914828|PMID:21857663
Molecular Function	GO:0005515	protein binding	Ly86	IPI	UniProtKB:Q62192	Mouse	MGI:MGI:1275858|PMID:9686597
Biological Process	GO:0051607	defense response to virus	ly86	IMP	ZFIN:ZDB-MRPHLNO-150709-1	Zfish	PMID:25681741
Biological Process	GO:0051607	defense response to virus	ly86	IGI	ZFIN:ZDB-MRPHLNO-150611-4,ZFIN:ZDB-MRPHLNO-150709-1	Zfish	PMID:25681741
Biological Process	GO:0045087	innate immune response	ly86	IMP		Zfish	PMID:27402697
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	Ly86	IGI	MGI:MGI:1194924	Mouse	PMID:10880523
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	Ly86	IDA		Mouse	PMID:10880523
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	Ly86	IGI	MGI:MGI:96824	Mouse	PMID:10880523
Biological Process	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	LY86	IGI	UniProtKB:Q99467	Human	PMID:10880523
Biological Process	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	Ly86	IGI	MGI:MGI:1194924	Mouse	PMID:10880523
Biological Process	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	Ly86	IDA		Mouse	PMID:10880523
Biological Process	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	Ly86	IGI	MGI:MGI:96824	Mouse	PMID:10880523
Biological Process	GO:0009615	response to virus	ly86	IMP		Zfish	PMID:27402697

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern