Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LTN1
  • Mouse genes Ltn1
  • Rat genes Ltn1
  • Zfish genes ltn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ltn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LTN1	IPI	UniProtKB:P58753	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	LTN1	IPI	UniProtKB:Q86WV6	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	LTN1	IPI	UniProtKB:Q92985	Human	PMID:21903422
Molecular Function	GO:0061630	ubiquitin protein ligase activity	LTN1	IDA		Human	PMID:25578875
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Ltn1	IDA		Mouse	PMID:19196968
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Ltn1	IDA		Mouse	MGI:MGI:3837634|PMID:19196968
Cellular Component	GO:0005829	cytosol	LTN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	LTN1	IDA		Human	PMID:25578875
Cellular Component	GO:0005829	cytosol	LTN1	IDA		Human	PMID:28757607
Cellular Component	GO:1990112	RQC complex	LTN1	IDA		Human	PMID:25578875
Biological Process	GO:0051865	protein autoubiquitination	Ltn1	IDA		Mouse	MGI:MGI:3837634|PMID:19196968
Biological Process	GO:1990116	ribosome-associated ubiquitin-dependent protein catabolic process	LTN1	IDA		Human	PMID:25578875

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern