Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LTBR
  • Mouse genes Ltbr
  • Rat genes Ltbr
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ltbr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	LTBR	IPI	UniProtKB:P36941	Human	PMID:20732415
Molecular Function	GO:0005515	protein binding	LTBR	IPI	UniProtKB:O43557	Human	PMID:12393901
Molecular Function	GO:0005515	protein binding	LTBR	IPI	UniProtKB:Q13114	Human	PMID:20732415
Molecular Function	GO:0005515	protein binding	LTBR	IPI	UniProtKB:Q15326	Human	PMID:20732415
Molecular Function	GO:0005515	protein binding	LTBR	IPI	UniProtKB:O43557	Human	PMID:26977880
Molecular Function	GO:0005515	protein binding	LTBR	IPI	UniProtKB:Q13114	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	LTBR	IPI	UniProtKB:Q08426	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LTBR	IPI	UniProtKB:Q9UI14	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LTBR	IPI	UniProtKB:P29846:PRO_0000037666	Human	PMID:8995654
Molecular Function	GO:0005515	protein binding	Ltbr	IPI	UniProtKB:P39429	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Ltbr	IPI	UniProtKB:O43557	Mouse	MGI:MGI:5774903|PMID:26977880
Molecular Function	GO:0005515	protein binding	Ltbr	IPI	UniProtKB:P39429	Mouse	MGI:MGI:5474156|PMID:23334419
Molecular Function	GO:0005515	protein binding	Ltbr	IPI	PR:P11679	Mouse	PMID:10747083
Molecular Function	GO:0005515	protein binding	Ltbr	IPI	PR:P05784	Mouse	PMID:10747083
Molecular Function	GO:0031625	ubiquitin protein ligase binding	LTBR	IPI	UniProtKB:O94972	Human	PMID:11279055
Molecular Function	GO:0031625	ubiquitin protein ligase binding	LTBR	IPI	UniProtKB:Q12933	Human	PMID:11279055
Cellular Component	GO:0005794	Golgi apparatus	LTBR	IDA		Human	GO_REF:0000052
Biological Process	GO:0071260	cellular response to mechanical stimulus	LTBR	IEP		Human	PMID:19593445
Biological Process	GO:0043011	myeloid dendritic cell differentiation	Ltbr	IMP	MGI:MGI:2384140	Mouse	PMID:23913046
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	LTBR	IMP		Human	PMID:20732415
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	LTBR	IEP		Human	PMID:12761501
Biological Process	GO:0046330	positive regulation of JNK cascade	LTBR	IMP		Human	PMID:20732415

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern