Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LTBP4
  • Mouse genes Ltbp4
  • Rat genes Ltbp4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ltbp4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LTBP4	IPI	UniProtKB:P35555	Human	PMID:12429738
Molecular Function	GO:0005515	protein binding	LTBP4	IPI	UniProtKB:P35555	Human	PMID:19349279
Molecular Function	GO:0005515	protein binding	LTBP4	IPI	UniProtKB:O00555	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	LTBP4	IPI	UniProtKB:O15265	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	LTBP4	IPI	UniProtKB:O95967	Human	PMID:27339457
Molecular Function	GO:0005515	protein binding	Ltbp4	IPI	UniProtKB:Q9WVH9|UniProtKB:Q9WVJ9|UniProtKB:Q9WVH9|UniProtKB:Q9WVJ9	Mouse	MGI:MGI:5638486|PMID:25713297
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP4	IPI	UniProtKB:P01137	Human	PMID:10930463
Molecular Function	GO:0050431	transforming growth factor beta binding	LTBP4	IDA		Human	PMID:9660815
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LTBP4	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LTBP4	IDA		Human	PMID:16157329
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LTBP4	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LTBP4	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LTBP4	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Ltbp4	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Ltbp4	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0031012	extracellular matrix	LTBP4	IDA		Human	PMID:9660815
Cellular Component	GO:0031012	extracellular matrix	Ltbp4	IDA		Mouse	PMID:12208849
Cellular Component	GO:0005576	extracellular region	LTBP4	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	LTBP4	HDA		Human	PMID:20551380
Cellular Component	GO:0001527	microfibril	Ltbp4	IDA		Mouse	MGI:MGI:4352793|PMID:19349279
Biological Process	GO:0048251	elastic fiber assembly	Ltbp4	IMP		Mouse	MGI:MGI:5638486|PMID:25713297
Biological Process	GO:0046879	hormone secretion	Ltbp4	IMP	MGI:MGI:2388061	Mouse	PMID:12208849
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Ltbp4	IMP	MGI:MGI:2388061	Mouse	PMID:12208849

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern