Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LSR
  • Mouse genes Lsr
  • Rat genes Lsr
  • Zfish genes lsr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lsr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Lsr	IPI	UniProtKB:Q3UZP0|UniProtKB:Q61146	Mouse	MGI:MGI:5507911|PMID:23239027
Molecular Function	GO:0005515	protein binding	Lsr	IPI	PR:Q91Y86	Mouse	PMID:24889144
Cellular Component	GO:0030054	cell junction	LSR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	LSR	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	LSR	HDA		Human	PMID:20458337
Cellular Component	GO:0005886	plasma membrane	LSR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Lsr	IDA		Mouse	MGI:MGI:3052428|PMID:15265030
Cellular Component	GO:0070160	tight junction	LSR	IDA		Human	PMID:23239027
Cellular Component	GO:0070160	tight junction	Lsr	IDA		Mouse	MGI:MGI:5507911|PMID:23239027
Cellular Component	GO:0061689	tricellular tight junction	Lsr	IDA		Mouse	MGI:MGI:5700290|PMID:22671589
Cellular Component	GO:0061689	tricellular tight junction	Lsr	IDA		Mouse	MGI:MGI:5700280|PMID:25753034
Cellular Component	GO:0061689	tricellular tight junction	Lsr	IDA		Mouse	MGI:MGI:6316553|PMID:21245199
Biological Process	GO:0007492	endoderm development	lsr	IMP	ZFIN:ZDB-MRPHLNO-080811-8	Zfish	PMID:18654634
Biological Process	GO:0007492	endoderm development	lsr	IMP	ZFIN:ZDB-MRPHLNO-080811-7	Zfish	PMID:18654634
Biological Process	GO:0010669	epithelial structure maintenance	Lsr	IDA		Mouse	MGI:MGI:5507911|PMID:23239027
Biological Process	GO:0060856	establishment of blood-brain barrier	Lsr	IMP		Mouse	MGI:MGI:5700280|PMID:25753034
Biological Process	GO:0061436	establishment of skin barrier	Lsr	IDA		Mouse	MGI:MGI:6316553|PMID:21245199
Biological Process	GO:0001889	liver development	Lsr	IMP		Mouse	MGI:MGI:3052428|PMID:15265030
Biological Process	GO:0031016	pancreas development	lsr	IMP	ZFIN:ZDB-MRPHLNO-080811-7	Zfish	PMID:18654634
Biological Process	GO:0031016	pancreas development	lsr	IMP	ZFIN:ZDB-MRPHLNO-080811-8	Zfish	PMID:18654634
Biological Process	GO:0061833	protein localization to tricellular tight junction	Lsr	IMP	UniProtKB:Q3UZP0	Mouse	MGI:MGI:6316553|PMID:21245199
Biological Process	GO:0019216	regulation of lipid metabolic process	Lsr	IDA		Rat	PMID:10224102|RGD:68812
Biological Process	GO:1904274	tricellular tight junction assembly	Lsr	IMP		Mouse	MGI:MGI:5700290|PMID:22671589
Biological Process	GO:1904274	tricellular tight junction assembly	Lsr	IDA		Mouse	MGI:MGI:6316553|PMID:21245199

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern