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Lsr Gene Detail
Summary
  • Symbol
    Lsr
  • Name
    lipolysis stimulated lipoprotein receptor
  • Synonyms
    ILDR3, Lisch7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927471
    NCBI Gene: 54135
  • Gene Overview
    MyGene.info: LSR
Location & Maps
more
  • Sequence Map
    Chr7:30957770-30973464 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      15695 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 19.27 cM, cytoband A3
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    LSR, lipolysis stimulated lipoprotein receptor
  • Vertebrate Orthologs
    8
  • Human Ortholog
    LSR, lipolysis stimulated lipoprotein receptor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ILDR3, LISCH7
  • Links
    NCBI Gene ID: 51599
    neXtProt AC: NX_Q86X29

  • Chr Location
    19q13.12; chr19:35248656-35267964 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9306
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: LSR
  • Gene Tree
    Lsr
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice display embryonic lethality during fetal growth and development, liver hypoplasia, and variable penetrance of pallor, hemorrhaging, superficial skin detachment, and reduced size.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022193 VEGA Gene Model | MGI Sequence Detail 15695 C57BL/6J ±  kb
transcript OTTMUST00000052721 VEGA | MGI Sequence Detail 2167 Not Applicable  
polypeptide OTTMUSP00000025036 VEGA | MGI Sequence Detail 594 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    172 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 8
    Primer pair 4

    Microarray probesets 3
References
more
  • Summaries
    All 43
    Developmental Gene Expression 12
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:20532 Lin Q, et al., Archaic structure of the gene encoding transcription factor USF. J Biol Chem. 1994 Sep 30;269(39):23894-903
  • Latest
    J:229257 Gu Z, et al., Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory