Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRRTM4
  • Mouse genes Lrrtm4
  • Rat genes Lrrtm4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrrtm4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043395	heparan sulfate proteoglycan binding	Lrrtm4	IDA		Mouse	PMID:23911104
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Lrrtm4	IDA		Mouse	PMID:22632720
Cellular Component	GO:0098982	GABA-ergic synapse	Lrrtm4	IDA		Mouse	PMID:31974009
Cellular Component	GO:0098978	glutamatergic synapse	Lrrtm4	IDA		Mouse	PMID:23911103
Cellular Component	GO:0098978	glutamatergic synapse	Lrrtm4	IMP		Mouse	PMID:23911103
Cellular Component	GO:0098978	glutamatergic synapse	Lrrtm4	IDA		Rat	PMID:23911103|RGD:13702303
Cellular Component	GO:0098684	photoreceptor ribbon synapse	Lrrtm4	IDA		Mouse	PMID:31974009
Cellular Component	GO:0098839	postsynaptic density membrane	Lrrtm4	IDA		Rat	PMID:23911103|RGD:13702303
Cellular Component	GO:0045211	postsynaptic membrane	Lrrtm4	IDA		Mouse	PMID:23911104
Cellular Component	GO:0045202	synapse	Lrrtm4	IDA		Mouse	PMID:31974009
Biological Process	GO:0097113	AMPA glutamate receptor clustering	Lrrtm4	IMP	MGI:MGI:5521326	Mouse	PMID:23911104
Biological Process	GO:0072578	neurotransmitter-gated ion channel clustering	Lrrtm4	IDA		Mouse	PMID:23911104
Biological Process	GO:0051965	positive regulation of synapse assembly	Lrrtm4	IDA		Mouse	PMID:24613359
Biological Process	GO:1901629	regulation of presynaptic membrane organization	Lrrtm4	IDA		Mouse	PMID:23911104
Biological Process	GO:0051963	regulation of synapse assembly	Lrrtm4	IDA		Mouse	PMID:23911103
Biological Process	GO:0051963	regulation of synapse assembly	Lrrtm4	IMP		Mouse	PMID:23911103
Biological Process	GO:0050808	synapse organization	Lrrtm4	IDA		Rat	PMID:19285470|RGD:8554788

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern