Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRRTM2
  • Mouse genes Lrrtm2
  • Rat genes Lrrtm2
  • Zfish genes lrrtm2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrrtm2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	lrrtm2	IDA		Zfish	PMID:19765300
Molecular Function	GO:0042043	neurexin family protein binding	Lrrtm2	IPI	UniProtKB:E9Q7X7	Rat	PMID:21424692|RGD:8554664
Molecular Function	GO:0042043	neurexin family protein binding	Lrrtm2	IPI	UniProtKB:Q9CS84	Rat	PMID:21424692|RGD:8554664
Molecular Function	GO:0005515	protein binding	LRRTM2	IPI	UniProtKB:A0PK00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LRRTM2	IPI	UniProtKB:P01375	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	lrrtm2	IPI	UniProtKB:A8BBG3	Zfish	PMID:19765300
Molecular Function	GO:0005515	protein binding	lrrtm2	IPI	UniProtKB:A8BB40	Zfish	PMID:19765300
Molecular Function	GO:0005515	protein binding	lrrtm2	IPI	UniProtKB:A8BB35	Zfish	PMID:19765300
Cellular Component	GO:0060076	excitatory synapse	Lrrtm2	IDA		Rat	PMID:19285470|RGD:8554788
Cellular Component	GO:0098982	GABA-ergic synapse	LRRTM2	IDA		Human	PMID:27565350
Cellular Component	GO:0098982	GABA-ergic synapse	LRRTM2	IMP		Human	PMID:27565350
Cellular Component	GO:0098978	glutamatergic synapse	Lrrtm2	IDA		Rat	PMID:19285470|RGD:8554788
Cellular Component	GO:0098978	glutamatergic synapse	Lrrtm2	IMP		Rat	PMID:19285470|RGD:8554788
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Lrrtm2	IDA		Rat	PMID:19285470|RGD:8554788
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Lrrtm2	IMP		Rat	PMID:19285470|RGD:8554788
Cellular Component	GO:0098839	postsynaptic density membrane	Lrrtm2	IDA		Rat	PMID:19285470|RGD:8554788
Cellular Component	GO:0098839	postsynaptic density membrane	Lrrtm2	IMP		Rat	PMID:19285470|RGD:8554788
Cellular Component	GO:0099634	postsynaptic specialization membrane	LRRTM2	IDA		Human	PMID:27565350
Cellular Component	GO:0099634	postsynaptic specialization membrane	LRRTM2	IMP		Human	PMID:27565350
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Lrrtm2	IDA		Rat	PMID:19285470|RGD:8554788
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Lrrtm2	IMP		Rat	PMID:19285470|RGD:8554788
Biological Process	GO:0060291	long-term synaptic potentiation	Lrrtm2	IGI	MGI:MGI:2389173	Mouse	PMID:23931994
Biological Process	GO:0002091	negative regulation of receptor internalization	Lrrtm2	IGI	MGI:MGI:2389173	Mouse	PMID:23931994
Biological Process	GO:0051965	positive regulation of synapse assembly	Lrrtm2	IDA		Mouse	PMID:24613359
Biological Process	GO:0099151	regulation of postsynaptic density assembly	Lrrtm2	IDA		Rat	PMID:19285470|RGD:8554788
Biological Process	GO:0099151	regulation of postsynaptic density assembly	Lrrtm2	IMP		Rat	PMID:19285470|RGD:8554788
Biological Process	GO:0050808	synapse organization	Lrrtm2	IGI	MGI:MGI:2179435	Mouse	PMID:21788371
Biological Process	GO:0050808	synapse organization	Lrrtm2	IGI	MGI:MGI:2444609	Mouse	PMID:21788371
Biological Process	GO:0050808	synapse organization	Lrrtm2	IGI	MGI:MGI:2389173	Mouse	PMID:21788371
Biological Process	GO:0050808	synapse organization	Lrrtm2	IDA		Rat	PMID:19285470|RGD:8554788

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern