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Lrrtm2
Gene Detail
Symbol

Name
ID
Lrrtm2
leucine rich repeat transmembrane neuronal 2
MGI:2389174
Synonyms
C630011A14Rik, mKIAA0416
Feature Type
protein coding gene
Genetic Map
Chromosome 18
18.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:35209011-35215024 bp, - strand
From Ensembl annotation of GRCm38

  6014 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:65342  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

HCOP human homology predictions: LRRTM2
Gene Tree: Lrrtm2

Human
homologs
LRRTM2, leucine rich repeat transmembrane neuronal 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 26045
neXtProt AC: NX_O43300

Human Chr (Location): 5q31.2; chr5:138869346-138875368 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Lrrtm2 interacts with 391 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process long-term synaptic potentiation, negative regulation of receptor internalization, ...
Component cell junction, excitatory synapse, ...
Function neurexin family protein binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (3)    Tissues (2)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 3
cDNA source data(16)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(20) cDNA(16) Primer pair(2) Other(2)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000071862 (Evidence)
Entrez Gene 107065 (Evidence)
UniGene 39900
DFCI TC1581215, TC1637288
NIA Mouse Gene Index U038319
Consensus CDS Project CCDS50251.1
International Mouse Phenotyping Consortium Status Lrrtm2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071862 Ensembl Gene Model | MGI Sequence Detail 6014 C57BL/6J ±  kb
transcript ENSMUST00000091636 Ensembl | MGI Sequence Detail 5665 Not Applicable 
polypeptide ENSMUSP00000089225 Ensembl | MGI Sequence Detail 515 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(42 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001611 Leucine-rich repeat
InterPro IPR025875 Leucine rich repeat 4
InterPro IPR000372 Leucine-rich repeat N-terminal domain
InterPro IPR003591 Leucine-rich repeat, typical subtype
Protein Ontology PR:000009947 leucine-rich repeat transmembrane neuronal protein 2
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:211830 Um JW, et al., Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. Cell Rep. 2014 Mar 27;6(6):1096-109
All references(32)
Other
accession IDs
MGI:2147278, MGI:2147387

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory