Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LPAR2
  • Mouse genes Lpar2
  • Rat genes Lpar2
  • Zfish genes lpar2a,lpar2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lpar2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070915	lysophosphatidic acid receptor activity	lpar2a	IDA		Zfish	PMID:21971049
Molecular Function	GO:0070915	lysophosphatidic acid receptor activity	lpar2b	IDA		Zfish	PMID:21971049
Molecular Function	GO:0030165	PDZ domain binding	Lpar2	IPI	UniProtKB:O15085	Mouse	PMID:15755723
Molecular Function	GO:0030165	PDZ domain binding	Lpar2	IPI	UniProtKB:Q9NZN5	Mouse	PMID:15755723
Molecular Function	GO:0005515	protein binding	LPAR2	IPI	UniProtKB:Q15654	Human	PMID:14688263
Molecular Function	GO:0005515	protein binding	LPAR2	IPI	UniProtKB:P13569	Human	PMID:16203867
Molecular Function	GO:0005515	protein binding	LPAR2	IPI	UniProtKB:Q15599	Human	PMID:16203867
Molecular Function	GO:0005515	protein binding	LPAR2	IPI	UniProtKB:P11233	Human	PMID:19306925
Molecular Function	GO:0005515	protein binding	LPAR2	IPI	UniProtKB:P25098	Human	PMID:19306925
Cellular Component	GO:0009986	cell surface	LPAR2	IDA		Human	PMID:19306925
Cellular Component	GO:0030139	endocytic vesicle	LPAR2	IDA		Human	PMID:19306925
Cellular Component	GO:0098978	glutamatergic synapse	Lpar2	IDA		Mouse	PMID:19766573
Cellular Component	GO:0048787	presynaptic active zone membrane	Lpar2	IDA		Mouse	PMID:19766573
Biological Process	GO:0001525	angiogenesis	lpar2a	IGI	ZFIN:ZDB-MRPHLNO-120123-7,ZFIN:ZDB-MRPHLNO-120123-8,ZFIN:ZDB-MRPHLNO-120202-2	Zfish	PMID:21971049
Biological Process	GO:0001525	angiogenesis	lpar2b	IGI	ZFIN:ZDB-MRPHLNO-120123-7,ZFIN:ZDB-MRPHLNO-120123-8,ZFIN:ZDB-MRPHLNO-120202-2	Zfish	PMID:21971049
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Lpar2	IDA		Mouse	PMID:15755723
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	lpar2a	IDA		Zfish	PMID:21971049|ZFIN:ZDB-PUB-111024-4
Biological Process	GO:0045647	negative regulation of erythrocyte differentiation	lpar2a	IMP	ZFIN:ZDB-MRPHLNO-120123-7	Zfish	PMID:27244685
Biological Process	GO:0043410	positive regulation of MAPK cascade	Lpar2	IDA		Mouse	PMID:15755723
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	Lpar2	IDA		Mouse	PMID:15755723
Biological Process	GO:0048916	posterior lateral line development	lpar2b	IMP	ZFIN:ZDB-MRPHLNO-180712-1	Zfish	PMID:29479307
Biological Process	GO:0002574	thrombocyte differentiation	lpar2a	IMP	ZFIN:ZDB-MRPHLNO-120123-7	Zfish	PMID:29239275

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern