Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LOXL1
  • Mouse genes Loxl1
  • Rat genes Loxl1
  • Zfish genes loxl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Loxl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	Loxl1	IDA		Mouse	PMID:15482472
Molecular Function	GO:0005515	protein binding	LOXL1	IPI	UniProtKB:O95967	Human	PMID:27339457
Molecular Function	GO:0005515	protein binding	Loxl1	IPI	PR:P54320	Mouse	PMID:16251195
Cellular Component	GO:0001669	acrosomal vesicle	Loxl1	IDA		Rat	PMID:22382377|RGD:7394733
Cellular Component	GO:0005604	basement membrane	Loxl1	IDA		Rat	PMID:22382377|RGD:7394733
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LOXL1	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LOXL1	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LOXL1	HDA		Human	PMID:27068509
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LOXL1	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Loxl1	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Loxl1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0005737	cytoplasm	Loxl1	IDA		Rat	PMID:22382377|RGD:7394733
Cellular Component	GO:0031012	extracellular matrix	Loxl1	IDA		Mouse	PMID:10022501
Cellular Component	GO:0031012	extracellular matrix	Loxl1	IDA		Rat	PMID:16251195|RGD:8553592
Cellular Component	GO:0005615	extracellular space	Loxl1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Biological Process	GO:0035904	aorta development	Loxl1	IEP		Rat	PMID:18803461|RGD:7394730
Biological Process	GO:0030903	notochord development	loxl1	IMP	ZFIN:ZDB-MRPHLNO-070818-1	Zfish	PMID:17543297
Biological Process	GO:0030903	notochord development	loxl1	IGI	ZFIN:ZDB-MRPHLNO-070818-2,ZFIN:ZDB-MRPHLNO-070919-6	Zfish	PMID:17543297
Biological Process	GO:0030903	notochord development	loxl1	IGI	ZFIN:ZDB-MRPHLNO-070818-2,ZFIN:ZDB-MRPHLNO-070919-4	Zfish	PMID:17543297
Biological Process	GO:0030903	notochord development	loxl1	IMP	ZFIN:ZDB-MRPHLNO-070818-2	Zfish	PMID:17543297
Biological Process	GO:0030903	notochord development	loxl1	IGI	ZFIN:ZDB-MRPHLNO-070818-3,ZFIN:ZDB-MRPHLNO-070919-5	Zfish	PMID:17543297
Biological Process	GO:0030903	notochord development	loxl1	IGI	ZFIN:ZDB-MRPHLNO-070818-1,ZFIN:ZDB-MRPHLNO-070919-4	Zfish	PMID:17543297
Biological Process	GO:0030903	notochord development	loxl1	IGI	ZFIN:ZDB-MRPHLNO-070818-1,ZFIN:ZDB-MRPHLNO-070919-6	Zfish	PMID:17543297
Biological Process	GO:0032496	response to lipopolysaccharide	Loxl1	IEP		Rat	PMID:19218354|RGD:7394732

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern