Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LNX2
  • Mouse genes Lnx2
  • Rat genes Lnx2
  • Zfish genes lnx2a,lnx2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lnx2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Lnx2	IPI	PR:Q91XL2	Mouse	PMID:11922143
Molecular Function	GO:0030165	PDZ domain binding	Lnx2	IDA		Mouse	PMID:11922143
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P45984	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q13163	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q86TG7	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q8WY64	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q96CV9	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q96EY7	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q96I15	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q9UHH9	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P03410	Human	PMID:22458338
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P0C206	Human	PMID:22458338
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P14079	Human	PMID:22458338
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q85601	Human	PMID:22458338
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P09022	Human	PMID:23088713
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q13643	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q96HT8	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P06576	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P45984	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q13163	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q86TG7	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q8IUZ5	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q8WY64	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q96CV9	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q96EY7	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q96I15	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q9H8K7	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q9UHH9	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P06576	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P45984	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q13163	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q86TG7	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q8IUZ5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q8WY64	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q96CV9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q96EY7	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q96I15	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q9H8K7	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q9UHH9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P00441	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P37173	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P45973	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LNX2	IPI	UniProtKB:K9N5R3	Human	PMID:33864728
Molecular Function	GO:0005515	protein binding	Lnx2	IPI	PR:Q9QZS3	Mouse	PMID:11922143
Molecular Function	GO:0005515	protein binding	Lnx2	IPI	PR:Q99P47	Mouse	PMID:25279559
Molecular Function	GO:0005515	protein binding	Lnx2	IPI	PR:Q91XL2	Mouse	PMID:11922143
Molecular Function	GO:0005515	protein binding	Lnx2	IPI	PR:P97792	Mouse	PMID:15979067
Molecular Function	GO:0005515	protein binding	Lnx2	IPI	PR:O70263	Mouse	PMID:11922143
Molecular Function	GO:0005515	protein binding	Lnx2	IPI	PR:P97792	Mouse	PMID:16410001
Molecular Function	GO:0005515	protein binding	lnx2b	IPI	UniProtKB:Q66K89	Zfish	PMID:21666599|ZFIN:ZDB-PUB-110628-8
Molecular Function	GO:0005515	protein binding	lnx2b	IPI	ZFIN:ZDB-GENE-990415-22	Zfish	PMID:19668196
Molecular Function	GO:0061630	ubiquitin protein ligase activity	lnx2a	IDA		Zfish	PMID:26392552
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	lnx2b	IDA		Zfish	PMID:19668196
Cellular Component	GO:0005886	plasma membrane	Lnx2	IDA		Mouse	PMID:25279559
Biological Process	GO:0031017	exocrine pancreas development	lnx2b	IGI	ZFIN:ZDB-GENO-160330-7,ZFIN:ZDB-MRPHLNO-160119-4	Zfish	PMID:26392552
Biological Process	GO:0031017	exocrine pancreas development	lnx2a	IMP	ZFIN:ZDB-GENO-160330-10	Zfish	PMID:26392552
Biological Process	GO:0031017	exocrine pancreas development	lnx2a	IMP	ZFIN:ZDB-MRPHLNO-160119-3	Zfish	PMID:26392552
Biological Process	GO:0031017	exocrine pancreas development	lnx2a	IGI	ZFIN:ZDB-GENO-160330-7,ZFIN:ZDB-MRPHLNO-160119-4	Zfish	PMID:26392552
Biological Process	GO:0061351	neural precursor cell proliferation	Lnx2	IMP		Mouse	PMID:25279559
Biological Process	GO:0030182	neuron differentiation	Lnx2	IDA		Mouse	PMID:25279559
Biological Process	GO:0070936	protein K48-linked ubiquitination	lnx2b	IDA		Zfish	PMID:19668196
Biological Process	GO:0016567	protein ubiquitination	lnx2a	IDA		Zfish	PMID:26392552|ZFIN:ZDB-PUB-150924-11
Biological Process	GO:0016567	protein ubiquitination	lnx2b	IPI	ZFIN:ZDB-GENE-990415-22	Zfish	PMID:19668196

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern