Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LIN7C
  • Mouse genes Lin7c
  • Rat genes Lin7c
  • Zfish genes lin7c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lin7c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008092	cytoskeletal protein binding	LIN7C	IPI	UniProtKB:O76041	Human	PMID:17987659
Molecular Function	GO:0097016	L27 domain binding	LIN7C	IDA		Human	PMID:20702775
Molecular Function	GO:0097016	L27 domain binding	lin7c	IPI	ZFIN:ZDB-GENE-020712-1	Zfish	PMID:19759292
Molecular Function	GO:0030165	PDZ domain binding	Lin7c	IPI	RGD:621660	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0030165	PDZ domain binding	Lin7c	IPI	RGD:62261	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0030165	PDZ domain binding	Lin7c	IPI	RGD:733316	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	LIN7C	IPI	UniProtKB:Q8N3R9	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	LIN7C	IPI	UniProtKB:Q13368	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	LIN7C	IPI	UniProtKB:Q5T2T1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	LIN7C	IPI	UniProtKB:Q9NZW5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	LIN7C	IPI	UniProtKB:P07947	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LIN7C	IPI	UniProtKB:Q13368	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LIN7C	IPI	UniProtKB:Q14168-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LIN7C	IPI	UniProtKB:Q5T2T1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LIN7C	IPI	UniProtKB:Q8N3R9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LIN7C	IPI	UniProtKB:Q9NZW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Lin7c	IPI	UniProtKB:Q08460	Mouse	MGI:MGI:3852248|PMID:19423573
Molecular Function	GO:0019904	protein domain specific binding	LIN7C	IPI	UniProtKB:Q5T2T1	Human	PMID:17237226
Cellular Component	GO:0005911	cell-cell junction	LIN7C	IDA		Human	PMID:23201090
Cellular Component	GO:0005911	cell-cell junction	Lin7c	IDA		Rat	PMID:10362251|RGD:633233
Cellular Component	GO:0005737	cytoplasm	LIN7C	IDA		Human	PMID:23201090
Cellular Component	GO:0098978	glutamatergic synapse	Lin7c	IDA		Mouse	PMID:16186258
Cellular Component	GO:0098978	glutamatergic synapse	Lin7c	IDA		Rat	PMID:10362251|RGD:633233
Cellular Component	GO:0016020	membrane	Lin7c	IDA		Rat	PMID:17084383|RGD:2326120
Cellular Component	GO:0097025	MPP7-DLG1-LIN7 complex	LIN7C	IDA		Human	PMID:20702775
Cellular Component	GO:0005886	plasma membrane	LIN7C	IDA		Human	PMID:23201090
Cellular Component	GO:0045202	synapse	Lin7c	IDA		Mouse	PMID:16186258
Cellular Component	GO:0045202	synapse	Lin7c	IDA		Rat	PMID:10362251|RGD:633233
Biological Process	GO:0045199	maintenance of epithelial cell apical/basal polarity	lin7c	IMP	ZFIN:ZDB-MRPHLNO-100513-8	Zfish	PMID:19759292
Biological Process	GO:0002011	morphogenesis of an epithelial sheet	LIN7C	IMP		Human	PMID:23201090
Biological Process	GO:0007269	neurotransmitter secretion	Lin7c	IGI	MGI:MGI:2135609	Mouse	PMID:16186258
Biological Process	GO:0007269	neurotransmitter secretion	Lin7c	IGI	MGI:MGI:1330858	Mouse	PMID:16186258

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern