Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CGB1,CGB2,CGB3,CGB5,CGB7,CGB8,LHB
  • Mouse genes Lhb
  • Rat genes Lhb
  • Zfish genes lhb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lhb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005179	hormone activity	CGB1	IMP		Human	PMID:19523396
Molecular Function	GO:0005179	hormone activity	CGB2	IMP		Human	PMID:19523396
Molecular Function	GO:0005179	hormone activity	lhb	IDA		Zfish	PMID:15728795
Molecular Function	GO:0005515	protein binding	LHB	IPI	UniProtKB:Q13643	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LHB	IPI	UniProtKB:Q96EQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LHB	IPI	UniProtKB:Q9P121-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CGB3	IPI	UniProtKB:P01215	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	CGB3	IPI	UniProtKB:P49901	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CGB3	IPI	UniProtKB:P01215	Human	PMID:7922031
Cellular Component	GO:0005737	cytoplasm	Lhb	IDA		Mouse	PMID:24739304
Cellular Component	GO:0061696	pituitary gonadotropin complex	CGB3	IPI		Human	PMID:7922031
Biological Process	GO:0008585	female gonad development	lhb	IGI	ZFIN:ZDB-GENE-040806-1	Zfish	PMID:26452104
Biological Process	GO:0035471	luteinizing hormone signaling pathway involved in ovarian follicle development	Lhb	IDA		Mouse	PMID:19474061
Biological Process	GO:0001556	oocyte maturation	lhb	IMP	ZFIN:ZDB-GENO-201007-1	Zfish	PMID:31322169
Biological Process	GO:0001556	oocyte maturation	lhb	IMP	ZFIN:ZDB-GENO-150429-3	Zfish	PMID:25396299
Biological Process	GO:0001556	oocyte maturation	lhb	IMP	ZFIN:ZDB-GENO-160127-5	Zfish	PMID:25584412
Biological Process	GO:0001556	oocyte maturation	lhb	IMP	ZFIN:ZDB-GENO-160127-1	Zfish	PMID:25238195
Biological Process	GO:1901360	organic cyclic compound metabolic process	Lhb	IDA		Mouse	PMID:26522847
Biological Process	GO:0030728	ovulation	lhb	IMP	ZFIN:ZDB-GENO-150429-3	Zfish	PMID:25396299
Biological Process	GO:0030728	ovulation	lhb	IMP	ZFIN:ZDB-GENO-160127-1	Zfish	PMID:25238195
Biological Process	GO:0007530	sex determination	lhb	IGI	ZFIN:ZDB-GENE-040806-1	Zfish	PMID:25396299
Biological Process	GO:0007283	spermatogenesis	lhb	IGI	ZFIN:ZDB-GENE-040806-1	Zfish	PMID:26452104

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern