Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LGI4
  • Mouse genes Lgi4
  • Rat genes Lgi4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lgi4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Lgi4	IPI	UniProtKB:Q9CPW0	Mouse	PMID:25707359
Molecular Function	GO:0005515	protein binding	Lgi4	IPI	PR:Q9R1V6	Mouse	PMID:20220021
Molecular Function	GO:0005515	protein binding	Lgi4	IPI	PR:Q9R1V6	Mouse	PMID:21068328
Molecular Function	GO:0005515	protein binding	Lgi4	IPI	PR:Q9R1V7	Mouse	PMID:21068328
Molecular Function	GO:0005515	protein binding	Lgi4	IPI	PR:Q9R1V4	Mouse	PMID:21068328
Cellular Component	GO:0005615	extracellular space	Lgi4	IDA		Mouse	PMID:16341215
Biological Process	GO:0008344	adult locomotory behavior	Lgi4	IMP	MGI:MGI:1856594	Mouse	PMID:1652607
Biological Process	GO:0021782	glial cell development	Lgi4	IMP	MGI:MGI:4439269	Mouse	PMID:21068328
Biological Process	GO:0014009	glial cell proliferation	Lgi4	IDA		Mouse	PMID:21068328
Biological Process	GO:0042063	gliogenesis	Lgi4	IMP	MGI:MGI:4439269	Mouse	PMID:21068328
Biological Process	GO:0042063	gliogenesis	Lgi4	IGI	MGI:MGI:1340046	Mouse	PMID:21068328
Biological Process	GO:0042552	myelination	Lgi4	IMP	MGI:MGI:1856594	Mouse	PMID:16341215
Biological Process	GO:0042552	myelination	Lgi4	IDA		Mouse	PMID:16341215
Biological Process	GO:0042552	myelination	Lgi4	IMP	MGI:MGI:1856594	Mouse	PMID:15282162
Biological Process	GO:0022011	myelination in peripheral nervous system	Lgi4	IMP	MGI:MGI:4359600,MGI:MGI:4441311	Mouse	PMID:20220021
Biological Process	GO:0022011	myelination in peripheral nervous system	Lgi4	IMP	MGI:MGI:1856594	Mouse	PMID:1652607
Biological Process	GO:0022011	myelination in peripheral nervous system	Lgi4	IMP	MGI:MGI:1856594	Mouse	PMID:9671673
Biological Process	GO:0022011	myelination in peripheral nervous system	Lgi4	IMP	MGI:MGI:4439269	Mouse	PMID:21068328
Biological Process	GO:0042551	neuron maturation	Lgi4	IMP	MGI:MGI:1856594	Mouse	PMID:15282162
Biological Process	GO:0031641	regulation of myelination	LGI4	IMP		Human	PMID:28318499
Biological Process	GO:0031641	regulation of myelination	Lgi4	IDA		Mouse	MGI:MGI:3614587|PMID:16341215
Biological Process	GO:0014044	Schwann cell development	Lgi4	IMP	MGI:MGI:4439269	Mouse	PMID:21068328

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern