Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LGALS8
  • Mouse genes Lgals8
  • Rat genes Lgals8
  • Zfish genes lgals8a,lgals8b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lgals8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030246	carbohydrate binding	LGALS8	IDA		Human	PMID:22246324
Molecular Function	GO:0030246	carbohydrate binding	Lgals8	IDA		Mouse	PMID:21753146
Molecular Function	GO:0005178	integrin binding	LGALS8	IPI	UniProtKB:P05556	Human	PMID:19268462
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:Q13137	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:Q15583	Human	PMID:18511908
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:Q86YL7	Human	PMID:19268462
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:Q13137	Human	PMID:22246324
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:P13798	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:P36406	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:Q13137	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:Q86VP1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:Q9UJV3-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:Q13137	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:P36406	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:Q13137	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:Q86VP1	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:P13798	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:Q13137	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LGALS8	IPI	UniProtKB:P0DTC2	Human	PMID:32915505
Cellular Component	GO:0005737	cytoplasm	LGALS8	IDA		Human	PMID:19268462
Cellular Component	GO:0005829	cytosol	LGALS8	IDA		Human	PMID:22246324
Cellular Component	GO:0016020	membrane	LGALS8	HDA		Human	PMID:19946888
Biological Process	GO:0098586	cellular response to virus	LGALS8	IMP		Human	PMID:28077878
Biological Process	GO:1904977	lymphatic endothelial cell migration	LGALS8	IDA		Human	PMID:19268462
Biological Process	GO:0002317	plasma cell differentiation	Lgals8	IDA		Mouse	PMID:21753146
Biological Process	GO:0031295	T cell costimulation	Lgals8	IDA		Mouse	PMID:22357632
Biological Process	GO:0098792	xenophagy	LGALS8	IMP		Human	PMID:22246324
Biological Process	GO:0098792	xenophagy	LGALS8	IMP		Human	PMID:28077878

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern