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Lgals8
Gene Detail
 Symbol
Name
ID
Lgals8
lectin, galactose binding, soluble 8
MGI:1928481
Synonyms 1200015E08Rik, D13Ertd524e, Lgals-8
Feature Type protein coding gene
Genetic Map
Chromosome 13
4.64 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr13:12439415-12464944 bp, - strand
From VEGA annotation of GRCm38

  25530 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31386  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: galectin
Gene Tree: Lgals8

Human
homologs
Human Homolog LGALS8, lectin, galactoside-binding, soluble, 8
NCBI Gene ID 3964
neXtProt AC  NX_O00214
Human Synonyms  Gal-8, PCTA1, PCTA-1, Po66-CBP
Human Chr (Location)  1q43; chr1:236518214-236552981 (+)  GRCh38
Alleles
and
phenotypes
All alleles(6) : Gene trapped(5) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in hyperactivity
 
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process plasma cell differentiation, T cell costimulation
Component cytoplasm, extracellular vesicular exosome, ...
Function carbohydrate binding
External Resources: FuncBase
Expression
cDNA source data(20)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(23) cDNA(20) Primer pair(3)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000033741 (Evidence)
Ensembl Gene ModelENSMUSG00000057554 (Evidence)
Entrez Gene56048 (Evidence)
DFCITC1574996, TC1596956, TC1683963, TC1700962
NIA Mouse Gene IndexU034513
Consensus CDS ProjectCCDS36592.1, CCDS70430.1, CCDS70431.1
International Mouse Knockout Project StatusLgals8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033741 VEGA Gene Model | MGI Sequence Detail 25530 C57BL/6J ±  kb
transcript OTTMUST00000085014 VEGA | MGI Sequence Detail 1148 Not Applicable 
polypeptide OTTMUSP00000045883 VEGA | MGI Sequence Detail 325 Not Applicable 

For the selected sequences
All sequences(97) RefSeq(24) UniProt(5)
Polymorphisms PCR(2) : SNPs within 2kb(187 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008985 Concanavalin A-like lectin/glucanases superfamily
InterPro IPR013320 Concanavalin A-like lectin/glucanase, subgroup
InterPro IPR001079 Galectin, carbohydrate recognition domain
Protein Ontology PR:000009775 galectin-8
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:183108 Tribulatti MV, et al., Redundant and antagonistic functions of galectin-1, -3, and -8 in the elicitation of T cell responses. J Immunol. 2012 Apr 1;188(7):2991-9
All references(37)
Other
accession IDs
MGI:1261882, MGI:1918987, MGI:2145217

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory