Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LDHC
  • Mouse genes Ldhc
  • Rat genes Ldhc
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ldhc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004459	L-lactate dehydrogenase activity	Ldhc	IMP	MGI:MGI:3775042	Mouse	PMID:18367675
Molecular Function	GO:0005515	protein binding	Ldhc	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Cellular Component	GO:0005929	cilium	Ldhc	IDA		Mouse	PMID:16687649
Cellular Component	GO:0005737	cytoplasm	Ldhc	IDA		Mouse	PMID:18367675
Cellular Component	GO:0005829	cytosol	Ldhc	IDA		Mouse	PMID:16582413
Cellular Component	GO:0070062	extracellular exosome	LDHC	HDA		Human	PMID:23533145
Cellular Component	GO:0031514	motile cilium	Ldhc	IDA		Mouse	PMID:18367675
Cellular Component	GO:0005634	nucleus	LDHC	HDA		Human	PMID:21630459
Biological Process	GO:0006754	ATP biosynthetic process	Ldhc	IMP	MGI:MGI:3775042	Mouse	PMID:18367675
Biological Process	GO:0030317	flagellated sperm motility	Ldhc	IMP	MGI:MGI:3775042	Mouse	PMID:18367675
Biological Process	GO:0019244	lactate biosynthetic process from pyruvate	Ldhc	IDA		Mouse	PMID:18367675
Biological Process	GO:0019516	lactate oxidation	Ldhc	IDA		Mouse	PMID:18367675
Biological Process	GO:0042867	pyruvate catabolic process	Ldhc	IMP	MGI:MGI:3775042	Mouse	PMID:21565994
Biological Process	GO:0006090	pyruvate metabolic process	Ldhc	IDA		Mouse	PMID:18367675

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern