Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LDB3
  • Mouse genes Ldb3
  • Rat genes Ldb3
  • Zfish genes ldb3a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ldb3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008092	cytoskeletal protein binding	LDB3	IPI	UniProtKB:O76041	Human	PMID:17987659
Molecular Function	GO:0019899	enzyme binding	Ldb3	IPI	RGD:3316	Rat	PMID:19377068|RGD:11069392
Molecular Function	GO:0051371	muscle alpha-actinin binding	Ldb3	IDA		Mouse	PMID:11696561
Molecular Function	GO:0005515	protein binding	LDB3	IPI	UniProtKB:P35609	Human	PMID:10427098
Molecular Function	GO:0005515	protein binding	LDB3	IPI	UniProtKB:Q8TDC0	Human	PMID:10427098
Molecular Function	GO:0005515	protein binding	LDB3	IPI	UniProtKB:Q9NP98	Human	PMID:10427098
Molecular Function	GO:0005515	protein binding	LDB3	IPI	UniProtKB:Q9NPC6	Human	PMID:10427098
Molecular Function	GO:0005515	protein binding	Ldb3	IPI	UniProtKB:Q9JI91	Mouse	MGI:MGI:1340723|PMID:10391924
Molecular Function	GO:0005515	protein binding	Ldb3	IPI	PR:Q8R4E4	Mouse	PMID:11842093
Molecular Function	GO:0005080	protein kinase C binding	Ldb3	IDA		Mouse	MGI:MGI:1340723|PMID:10391924
Cellular Component	GO:0005856	cytoskeleton	LDB3	IDA		Human	PMID:10427098
Cellular Component	GO:0030018	Z disc	LDB3	IDA		Human	PMID:10427098
Cellular Component	GO:0030018	Z disc	Ldb3	IDA		Mouse	PMID:19047374
Cellular Component	GO:0030018	Z disc	Ldb3	IDA		Mouse	PMID:16481394
Cellular Component	GO:0030018	Z disc	Ldb3	IDA		Rat	PMID:19377068|RGD:11069392
Biological Process	GO:0007507	heart development	ldb3a	IMP	ZFIN:ZDB-MRPHLNO-061221-2	Zfish	PMID:16982050
Biological Process	GO:0007507	heart development	ldb3a	IMP	ZFIN:ZDB-MRPHLNO-061221-1	Zfish	PMID:16982050
Biological Process	GO:0007626	locomotory behavior	ldb3a	IMP	ZFIN:ZDB-MRPHLNO-061221-1	Zfish	PMID:25866181
Biological Process	GO:0045214	sarcomere organization	Ldb3	IMP	MGI:MGI:2652058	Mouse	PMID:11696561
Biological Process	GO:0007519	skeletal muscle tissue development	ldb3a	IMP	ZFIN:ZDB-MRPHLNO-061221-1	Zfish	PMID:25866181
Biological Process	GO:0001756	somitogenesis	ldb3a	IMP	ZFIN:ZDB-MRPHLNO-061221-1	Zfish	PMID:16982050
Biological Process	GO:0001756	somitogenesis	ldb3a	IMP	ZFIN:ZDB-MRPHLNO-061221-2	Zfish	PMID:16982050

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern