Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LAT2
  • Mouse genes Lat2
  • Rat genes Lat2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lat2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LAT2	IPI	UniProtKB:P62993	Human	PMID:14722116
Molecular Function	GO:0042169	SH2 domain binding	LAT2	IMP		Human	PMID:14722116
Molecular Function	GO:0042169	SH2 domain binding	LAT2	IPI	UniProtKB:Q9ULZ2	Human	PMID:20442417
Cellular Component	GO:0070062	extracellular exosome	LAT2	HDA		Human	PMID:20458337
Cellular Component	GO:0045121	membrane raft	LAT2	IDA		Human	PMID:12486104
Cellular Component	GO:0045121	membrane raft	LAT2	IDA		Human	PMID:12514734
Cellular Component	GO:0005886	plasma membrane	LAT2	IDA		Human	GO_REF:0000052
Biological Process	GO:0042113	B cell activation	LAT2	IDA		Human	PMID:12514734
Biological Process	GO:0050853	B cell receptor signaling pathway	LAT2	IDA		Human	PMID:12514734
Biological Process	GO:0019722	calcium-mediated signaling	LAT2	IGI		Human	PMID:14722116
Biological Process	GO:0035556	intracellular signal transduction	LAT2	IGI		Human	PMID:14722116

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern