Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LAMC2
  • Mouse genes Lamc2
  • Rat genes Lamc2
  • Zfish genes lamc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lamc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008201	heparin binding	Lamc2	IDA		Mouse	PMID:11733994
Molecular Function	GO:0005515	protein binding	Lamc2	IPI	PR:P37889	Mouse	PMID:11733994
Molecular Function	GO:0005515	protein binding	Lamc2	IPI	PR:P10493	Mouse	PMID:11733994
Cellular Component	GO:0005604	basement membrane	Lamc2	IDA		Mouse	PMID:9264260
Cellular Component	GO:0005604	basement membrane	Lamc2	IDA		Mouse	PMID:15895400
Cellular Component	GO:0005604	basement membrane	Lamc2	IDA		Mouse	PMID:18757743
Cellular Component	GO:0005604	basement membrane	Lamc2	IDA		Mouse	PMID:11733994
Cellular Component	GO:0005938	cell cortex	Lamc2	IDA		Rat	PMID:16409251|RGD:1581345
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMC2	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	LAMC2	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Lamc2	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0031012	extracellular matrix	Lamc2	IDA		Rat	PMID:9417868|RGD:633095
Cellular Component	GO:0005615	extracellular space	Lamc2	IDA		Rat	PMID:16409251|RGD:1581345
Cellular Component	GO:0005607	laminin-2 complex	Lamc2	IDA		Rat	PMID:9417868|RGD:633095
Cellular Component	GO:0005610	laminin-5 complex	Lamc2	IDA		Mouse	PMID:9264260
Cellular Component	GO:0016020	membrane	Lamc2	IDA		Rat	PMID:16409251|RGD:1581345
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Lamc2	IDA		Rat	PMID:16409251|RGD:1581345
Biological Process	GO:0030335	positive regulation of cell migration	LAMC2	IMP		Human	PMID:24091622
Biological Process	GO:0008284	positive regulation of cell population proliferation	LAMC2	IMP		Human	PMID:24091622

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern