Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KSR2
  • Mouse genes Ksr2
  • Rat genes Ksr2
  • Zfish genes ksr2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ksr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005078	MAP-kinase scaffold activity	Ksr2	IDA		Mouse	PMID:19560418
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	Ksr2	IDA		Mouse	PMID:19560418
Molecular Function	GO:0005515	protein binding	KSR2	IPI	UniProtKB:P07900	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	KSR2	IPI	UniProtKB:Q13451	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	KSR2	IPI	UniProtKB:Q16543	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	KSR2	IPI	UniProtKB:P07900	Human	PMID:27086506
Molecular Function	GO:0005515	protein binding	KSR2	IPI	UniProtKB:Q13451	Human	PMID:27086506
Molecular Function	GO:0005515	protein binding	KSR2	IPI	UniProtKB:Q16543	Human	PMID:27086506
Molecular Function	GO:0005515	protein binding	KSR2	IPI	UniProtKB:P15056	Human	PMID:29433126
Molecular Function	GO:0005515	protein binding	KSR2	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KSR2	IPI	UniProtKB:P07900	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	KSR2	IPI	UniProtKB:Q13451	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	KSR2	IPI	UniProtKB:Q16543	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Ksr2	IPI	PR:P63328	Mouse	PMID:19560418
Cellular Component	GO:0005829	cytosol	Ksr2	IDA		Mouse	PMID:19560418
Cellular Component	GO:0005886	plasma membrane	Ksr2	IDA		Mouse	PMID:19560418
Biological Process	GO:0019722	calcium-mediated signaling	Ksr2	IGI	MGI:MGI:107164	Mouse	PMID:19560418
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Ksr2	IMP		Mouse	MGI:MGI:6162304|PMID:28180061
Biological Process	GO:0043410	positive regulation of MAPK cascade	Ksr2	IDA		Mouse	PMID:19560418

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern