Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KRT6A,KRT6B,KRT6C
  • Mouse genes Krt6b
  • Rat genes LOC683313
  • Zfish genes krt4,krt5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Krt6b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q9BT92	Human	PMID:15731013
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P19012	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q15834	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:A1A4E9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:O14964	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:O43765	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:O76015	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P19012	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P36406	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q9UBB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:F5H3M2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:O76015	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P13646	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P19012	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P36406	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q08379	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q15323	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q6A162	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q9BYV2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q9UBB9	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:O14964	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P19012	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q6A162	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:O76015	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:O76015	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P13646	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P19012	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q08379	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q9BYV2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q9UBB9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:O76013-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:O76015	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P05783	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P08727	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P08779	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P13646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P19012	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P37198	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P55040	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P61601	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q7Z3Y7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q7Z3Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q7Z3Y9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q7Z3Z0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q8N3L3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q92764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q9BXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q9BYV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6A	IPI	UniProtKB:P07237	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:P08727	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:P19012	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:A1A4E9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:O14777	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:O76015	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:P19012	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q9UBB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:O43482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:O76014	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:O76015	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:P08727	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:P13646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:P19012	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:P37198	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q14525	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q6A163	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q7Z3Y7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q7Z3Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q7Z3Z0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q8IYF3-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q92764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q9BYV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q9UBB9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6B	IPI	UniProtKB:Q9UGJ1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:A1A4E9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:O76015	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:P19012	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q9UBB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:P05783	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:O76013-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:O76014	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:O76015	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:P02533	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:P05783	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:P08727	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:P08779	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q08043	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q14525	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q2M2I5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q7Z3Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q7Z3Y9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q7Z3Z0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q92764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT6C	IPI	UniProtKB:Q9BYV2	Human	PMID:32296183
Cellular Component	GO:0070062	extracellular exosome	KRT6A	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	KRT6A	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	KRT6B	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	KRT6C	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	KRT6A	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	KRT6A	HDA		Human	PMID:21630459
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	KRT6A	IDA		Human	PMID:23006328
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	KRT6A	IMP		Human	PMID:23006328
Biological Process	GO:0050830	defense response to Gram-positive bacterium	KRT6A	IDA		Human	PMID:23006328
Biological Process	GO:0050830	defense response to Gram-positive bacterium	KRT6A	IMP		Human	PMID:23006328
Biological Process	GO:0031101	fin regeneration	krt5	IEP		Zfish	PMID:22278371
Biological Process	GO:0045104	intermediate filament cytoskeleton organization	KRT6C	IMP		Human	PMID:23662636
Biological Process	GO:0045109	intermediate filament organization	Krt6b	IGI	MGI:MGI:96691	Mouse	PMID:15601842
Biological Process	GO:0045109	intermediate filament organization	Krt6b	IGI	MGI:MGI:1100845	Mouse	PMID:15601842
Biological Process	GO:0031424	keratinization	Krt6b	IGI	MGI:MGI:1100845	Mouse	PMID:15601842
Biological Process	GO:0031424	keratinization	Krt6b	IGI	MGI:MGI:96691	Mouse	PMID:15601842
Biological Process	GO:0031640	killing of cells of another organism	KRT6A	IDA		Human	PMID:23006328
Biological Process	GO:0031640	killing of cells of another organism	KRT6A	IMP		Human	PMID:23006328
Biological Process	GO:0002009	morphogenesis of an epithelium	Krt6b	IGI	MGI:MGI:96691	Mouse	PMID:15601842
Biological Process	GO:0002009	morphogenesis of an epithelium	Krt6b	IGI	MGI:MGI:1100845	Mouse	PMID:15601842
Biological Process	GO:2000536	negative regulation of entry of bacterium into host cell	KRT6A	IDA		Human	PMID:23006328

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern