Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KDM4C
  • Mouse genes Kdm4c
  • Rat genes
  • Zfish genes kdm4c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kdm4c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	KDM4C	IPI	UniProtKB:O60341	Human	PMID:17277772
Molecular Function	GO:0019899	enzyme binding	Kdm4c	IPI	UniProtKB:Q6ZQ88	Mouse	MGI:MGI:4943397|PMID:17277772
Molecular Function	GO:0032452	histone demethylase activity	KDM4C	EXP		Human	PMID:18066052
Molecular Function	GO:0032452	histone demethylase activity	Kdm4c	IDA		Mouse	PMID:19144645
Molecular Function	GO:0051864	histone H3K36 demethylase activity	KDM4C	IDA		Human	PMID:21914792
Molecular Function	GO:0032454	histone H3K9 demethylase activity	KDM4C	IMP		Human	PMID:17277772
Molecular Function	GO:0032454	histone H3K9 demethylase activity	KDM4C	IDA		Human	PMID:18066052
Molecular Function	GO:0032454	histone H3K9 demethylase activity	KDM4C	IMP		Human	PMID:28262558
Molecular Function	GO:0032454	histone H3K9 demethylase activity	Kdm4c	IDA		Mouse	PMID:16738407
Molecular Function	GO:0032454	histone H3K9 demethylase activity	Kdm4c	IMP		Mouse	PMID:17938240
Molecular Function	GO:0140684	histone H3K9me2/H3K9me3 demethylase activity	KDM4C	IDA		Human	PMID:21914792
Molecular Function	GO:0050681	nuclear androgen receptor binding	KDM4C	IPI	UniProtKB:P10275	Human	PMID:17277772
Molecular Function	GO:0050681	nuclear androgen receptor binding	Kdm4c	IPI	UniProtKB:P19091	Mouse	MGI:MGI:4943397|PMID:17277772
Molecular Function	GO:0008270	zinc ion binding	KDM4C	IDA		Human	PMID:21914792
Cellular Component	GO:0000785	chromatin	KDM4C	IDA		Human	PMID:17277772
Cellular Component	GO:0005721	pericentric heterochromatin	Kdm4c	IDA		Mouse	PMID:16738407
Biological Process	GO:0001825	blastocyst formation	Kdm4c	IMP		Mouse	PMID:19696013
Biological Process	GO:0048514	blood vessel morphogenesis	kdm4c	IMP	ZFIN:ZDB-MRPHLNO-141120-32	Zfish	PMID:26120059
Biological Process	GO:0033169	histone H3-K9 demethylation	KDM4C	IMP		Human	PMID:17277772
Biological Process	GO:0016570	histone modification	Kdm4c	IDA		Mouse	MGI:MGI:3845989|PMID:19144645
Biological Process	GO:0008284	positive regulation of cell population proliferation	KDM4C	IMP		Human	PMID:17277772
Biological Process	GO:0010468	regulation of gene expression	Kdm4c	IMP		Mouse	PMID:17938240
Biological Process	GO:0010468	regulation of gene expression	Kdm4c	IMP		Mouse	PMID:19696013
Biological Process	GO:2000736	regulation of stem cell differentiation	Kdm4c	IDA		Mouse	PMID:17938240
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	KDM4C	IDA		Human	PMID:17277772
Biological Process	GO:0019827	stem cell population maintenance	Kdm4c	IGI	MGI:MGI:1919200	Mouse	PMID:17938240

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern