Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCTD15
  • Mouse genes Kctd15
  • Rat genes Kctd15
  • Zfish genes kctd15a,kctd15b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kctd15

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	KCTD15	IPI	UniProtKB:Q96SI1	Human	PMID:27152988
Molecular Function	GO:0005515	protein binding	KCTD15	IPI	UniProtKB:Q719H9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD15	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Cellular Component	GO:0005634	nucleus	Kctd15	IDA		Mouse	MGI:MGI:6210177|PMID:25187989
Biological Process	GO:0007420	brain development	kctd15b	IGI	ZFIN:ZDB-GENO-180711-4	Zfish	PMID:29216270
Biological Process	GO:0007420	brain development	kctd15a	IGI	ZFIN:ZDB-GENO-180711-4	Zfish	PMID:29216270
Biological Process	GO:0060070	canonical Wnt signaling pathway	kctd15a	IGI	ZFIN:ZDB-MRPHLNO-100908-5,ZFIN:ZDB-MRPHLNO-100908-6	Zfish	PMID:20685732
Biological Process	GO:0060070	canonical Wnt signaling pathway	kctd15b	IGI	ZFIN:ZDB-MRPHLNO-100908-5,ZFIN:ZDB-MRPHLNO-100908-6	Zfish	PMID:20685732
Biological Process	GO:0014033	neural crest cell differentiation	kctd15b	IGI	ZFIN:ZDB-GENO-180711-4	Zfish	PMID:29216270
Biological Process	GO:0014033	neural crest cell differentiation	kctd15a	IGI	ZFIN:ZDB-GENO-180711-4	Zfish	PMID:29216270
Biological Process	GO:0060037	pharyngeal system development	kctd15b	IGI	ZFIN:ZDB-MRPHLNO-100908-5,ZFIN:ZDB-MRPHLNO-100908-6	Zfish	PMID:20685732
Biological Process	GO:0060037	pharyngeal system development	kctd15a	IGI	ZFIN:ZDB-MRPHLNO-100908-5,ZFIN:ZDB-MRPHLNO-100908-6	Zfish	PMID:20685732
Biological Process	GO:2001141	regulation of RNA biosynthetic process	kctd15a	IDA		Zfish	PMID:23382213

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern