Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ITLN1
  • Mouse genes Itlnb
  • Rat genes Itln1
  • Zfish genes itln2,si:ch211-194p6.12
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Itlnb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	ITLN1	IDA		Human	PMID:26148048
Molecular Function	GO:0042802	identical protein binding	ITLN1	IPI	UniProtKB:Q8WWA0	Human	PMID:26148048
Molecular Function	GO:0070492	oligosaccharide binding	ITLN1	IDA		Human	PMID:26148048
Molecular Function	GO:0005515	protein binding	ITLN1	IPI	UniProtKB:Q6UWW9	Human	PMID:26819645
Molecular Function	GO:0042803	protein homodimerization activity	itln2	IDA		Zfish	PMID:35337980
Cellular Component	GO:0070062	extracellular exosome	ITLN1	HDA		Human	PMID:19056867
Cellular Component	GO:0005615	extracellular space	Itlnb	IDA		Mouse	PMID:15265922
Cellular Component	GO:0043235	receptor complex	ITLN1	IDA		Human	PMID:23382219
Biological Process	GO:0002215	defense response to nematode	Itlnb	IMP		Mouse	PMID:15265922
Biological Process	GO:0043152	induction of bacterial agglutination	itln2	IDA		Zfish	PMID:27329687
Biological Process	GO:0046326	positive regulation of glucose import	ITLN1	IDA		Human	PMID:16531507
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ITLN1	IDA		Human	PMID:16531507
Biological Process	GO:0070207	protein homotrimerization	ITLN1	IDA		Human	PMID:26148048
Biological Process	GO:0009624	response to nematode	Itlnb	IDA		Mouse	MGI:MGI:3768197|PMID:17420014
Biological Process	GO:0009624	response to nematode	Itlnb	IDA		Mouse	MGI:MGI:3768628|PMID:15048991

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern