Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ITGA7
  • Mouse genes Itga7
  • Rat genes Itga7
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Itga7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	Itga7	IDA		Rat	PMID:1315319|RGD:70774
Molecular Function	GO:0005178	integrin binding	Itga7	IPI	RGD:2927	Rat	PMID:1315319|RGD:70774
Molecular Function	GO:0043236	laminin binding	Itga7	IDA		Mouse	PMID:1839357
Molecular Function	GO:0043236	laminin binding	Itga7	IMP		Mouse	PMID:9004048
Molecular Function	GO:0043236	laminin binding	Itga7	IDA		Rat	PMID:1315319|RGD:70774
Molecular Function	GO:0043236	laminin binding	Itga7	IDA		Rat	PMID:16282198|RGD:1600026
Molecular Function	GO:0005515	protein binding	ITGA7	IPI	UniProtKB:O75838	Human	PMID:22779914
Molecular Function	GO:0005515	protein binding	Itga7	IPI	UniProtKB:Q6A028|UniProtKB:Q8C2K1	Mouse	MGI:MGI:3715039|PMID:17403664
Molecular Function	GO:0005515	protein binding	Itga7	IPI	PR:Q9Z309	Mouse	PMID:18611855
Molecular Function	GO:0005515	protein binding	Itga7	IPI	UniProtKB:P35444	Rat	PMID:20019333|RGD:8554850
Molecular Function	GO:0044877	protein-containing complex binding	Itga7	IDA		Rat	PMID:1315319|RGD:70774
Cellular Component	GO:0009986	cell surface	Itga7	IDA		Rat	PMID:1315319|RGD:70774
Cellular Component	GO:0005737	cytoplasm	Itga7	IDA		Mouse	PMID:19796622
Cellular Component	GO:0034677	integrin alpha7-beta1 complex	Itga7	IDA		Mouse	PMID:18611855
Cellular Component	GO:0034677	integrin alpha7-beta1 complex	Itga7	IPI	PR:P09055	Mouse	PMID:1839357
Cellular Component	GO:0008305	integrin complex	Itga7	IDA		Rat	PMID:1315319|RGD:70774
Cellular Component	GO:0005927	muscle tendon junction	Itga7	IDA		Mouse	PMID:18611855
Cellular Component	GO:0031594	neuromuscular junction	Itga7	IDA		Mouse	PMID:18611855
Cellular Component	GO:0042383	sarcolemma	Itga7	IDA		Mouse	PMID:18611855
Biological Process	GO:0048514	blood vessel morphogenesis	Itga7	IMP	MGI:MGI:3512077	Mouse	PMID:16003770
Biological Process	GO:0007155	cell adhesion	Itga7	IMP		Mouse	PMID:9004048
Biological Process	GO:0007155	cell adhesion	Itga7	IDA		Rat	PMID:1315319|RGD:70774
Biological Process	GO:0007155	cell adhesion	Itga7	IMP		Rat	PMID:16282198|RGD:1600026
Biological Process	GO:0016477	cell migration	Itga7	IMP		Mouse	PMID:9004048
Biological Process	GO:0035987	endodermal cell differentiation	ITGA7	IEP		Human	PMID:23154389
Biological Process	GO:0034113	heterotypic cell-cell adhesion	ITGA7	IMP		Human	PMID:20563599
Biological Process	GO:0007229	integrin-mediated signaling pathway	Itga7	IDA		Rat	PMID:1315319|RGD:70774
Biological Process	GO:0007519	skeletal muscle tissue development	Itga7	IEP		Rat	PMID:1315319|RGD:70774

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern