Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IRF9
  • Mouse genes Irf9
  • Rat genes Irf9
  • Zfish genes irf9
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Irf9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	IRF9	IPI	UniProtKB:P48551	Human	PMID:17923090
Molecular Function	GO:0005515	protein binding	IRF9	IPI	UniProtKB:P52630	Human	PMID:17923090
Molecular Function	GO:0005515	protein binding	IRF9	IPI	UniProtKB:P52630	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	IRF9	IPI	UniProtKB:P52630	Human	PMID:24065129
Molecular Function	GO:0005515	protein binding	IRF9	IPI	UniProtKB:P52630	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Irf9	IPI	UniProtKB:Q15327	Mouse	MGI:MGI:5294529|PMID:20599664
Molecular Function	GO:0005515	protein binding	Irf9	IPI	UniProtKB:Q9QXJ2	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0005515	protein binding	Irf9	IPI	UniProtKB:Q9QXJ2	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IRF9	IMP		Human	PMID:24882218
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	IRF9	IDA		Human	PMID:28473536
Cellular Component	GO:0005829	cytosol	IRF9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070721	ISGF3 complex	IRF9	IPI		Human	PMID:24065129
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IRF9	IDA		Human	PMID:24065129
Biological Process	GO:0032606	type I interferon production	Irf9	IMP	MGI:MGI:2446102	Mouse	PMID:15800576

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern