Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IRAG1
  • Mouse genes Irag1
  • Rat genes Irag1
  • Zfish genes mrvi1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Irag1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	IRAG1	IPI	UniProtKB:Q13976	Human	PMID:16990611
Molecular Function	GO:0005515	protein binding	Irag1	IPI	PR:P11881	Mouse	PMID:15483626
Molecular Function	GO:0005515	protein binding	Irag1	IPI	PR:P0C605	Mouse	PMID:15483626
Biological Process	GO:0019934	cGMP-mediated signaling	Irag1	IMP	MGI:MGI:3525059	Mouse	PMID:15483626
Biological Process	GO:0045986	negative regulation of smooth muscle contraction	Irag1	IMP	MGI:MGI:3525059	Mouse	PMID:15483626
Biological Process	GO:0060087	relaxation of vascular associated smooth muscle	Irag1	IMP	MGI:MGI:3525059	Mouse	PMID:15483626

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern