Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes INPP5J
  • Mouse genes Inpp5j
  • Rat genes Inpp5j
  • Zfish genes inpp5jb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Inpp5j

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004445	inositol-polyphosphate 5-phosphatase activity	Inpp5j	IDA		Rat	PMID:10593988|RGD:633686
Molecular Function	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	Inpp5j	IDA		Mouse	PMID:16280363
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:P14373	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q12929	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q96EY1-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q9UJX2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:P31321	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:P50221	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:P51116	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:P61289	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q5JST6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q6NUQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q8NHQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q96FA3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q9BYV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5J	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	INPP5J	IDA		Human	PMID:12536145
Cellular Component	GO:0005737	cytoplasm	Inpp5j	IDA		Rat	PMID:16280363|RGD:2312436
Cellular Component	GO:0043198	dendritic shaft	Inpp5j	IDA		Mouse	PMID:16280363
Cellular Component	GO:0030426	growth cone	Inpp5j	IDA		Mouse	PMID:16280363
Cellular Component	GO:0030426	growth cone	Inpp5j	IDA		Rat	PMID:16280363|RGD:2312436
Cellular Component	GO:0005886	plasma membrane	Inpp5j	IDA		Mouse	PMID:16280363
Cellular Component	GO:0001726	ruffle	INPP5J	IDA		Human	PMID:12536145
Cellular Component	GO:0001726	ruffle	Inpp5j	IDA		Rat	PMID:10593988|RGD:633686
Cellular Component	GO:0032587	ruffle membrane	Inpp5j	IDA		Rat	PMID:10593988|RGD:633686
Biological Process	GO:0031115	negative regulation of microtubule polymerization	Inpp5j	IMP		Rat	PMID:16280363|RGD:2312436
Biological Process	GO:0010977	negative regulation of neuron projection development	Inpp5j	IMP		Mouse	PMID:16280363
Biological Process	GO:0010977	negative regulation of neuron projection development	Inpp5j	IDA		Mouse	PMID:16280363
Biological Process	GO:0010977	negative regulation of neuron projection development	Inpp5j	IMP		Rat	PMID:16280363|RGD:2312436
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	Inpp5j	IDA		Mouse	PMID:16280363
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	Inpp5j	IMP		Mouse	PMID:16280363

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern