Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IL11RA
  • Mouse genes Il11ra1
  • Rat genes Il11ra1
  • Zfish genes il11ra
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Il11ra1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019970	interleukin-11 binding	Il11ra1	IPI	PR:P47873	Mouse	PMID:7957045
Molecular Function	GO:0004921	interleukin-11 receptor activity	IL11RA	IDA		Human	PMID:8637716
Molecular Function	GO:0004921	interleukin-11 receptor activity	Il11ra1	IDA		Mouse	PMID:7957045
Molecular Function	GO:0005515	protein binding	IL11RA	IPI	UniProtKB:Q6UX06	Human	PMID:32296183
Biological Process	GO:0008283	cell population proliferation	Il11ra1	IDA		Mouse	PMID:7957045
Biological Process	GO:0019221	cytokine-mediated signaling pathway	Il11ra1	IDA		Mouse	PMID:7957045
Biological Process	GO:0046697	decidualization	Il11ra1	IMP	MGI:MGI:2177778	Mouse	PMID:9500603
Biological Process	GO:0046697	decidualization	Il11ra1	IMP	MGI:MGI:2177774	Mouse	PMID:9679067
Biological Process	GO:0032502	developmental process	IL11RA	IMP		Human	PMID:21741611
Biological Process	GO:0007566	embryo implantation	Il11ra1	IMP		Rat	PMID:11570967|RGD:1302225
Biological Process	GO:0060322	head development	IL11RA	IMP		Human	PMID:21741611
Biological Process	GO:0038154	interleukin-11-mediated signaling pathway	IL11RA	IDA		Human	PMID:8637716
Biological Process	GO:0060135	maternal process involved in female pregnancy	Il11ra1	IMP	MGI:MGI:2177778	Mouse	PMID:9500603
Biological Process	GO:0060135	maternal process involved in female pregnancy	Il11ra1	IMP	MGI:MGI:2177774	Mouse	PMID:9679067
Biological Process	GO:0001779	natural killer cell differentiation	Il11ra1	IMP	MGI:MGI:2177774	Mouse	PMID:15499555
Biological Process	GO:0001890	placenta development	Il11ra1	IMP	MGI:MGI:2177774	Mouse	PMID:9679067
Biological Process	GO:0008284	positive regulation of cell population proliferation	Il11ra1	IDA		Mouse	PMID:7957045

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern