Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IGF2BP2
  • Mouse genes Igf2bp2
  • Rat genes Igf2bp2
  • Zfish genes igf2bp2a,igf2bp2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Igf2bp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003730	mRNA 3'-UTR binding	IGF2BP2	IDA		Human	PMID:20080952
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Igf2bp2	IDA		Mouse	PMID:25863250
Molecular Function	GO:0048027	mRNA 5'-UTR binding	IGF2BP2	IDA		Human	PMID:9891060
Molecular Function	GO:0048027	mRNA 5'-UTR binding	Igf2bp2	IDA		Mouse	PMID:25863250
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	IGF2BP2	IDA		Human	PMID:29476152
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	IGF2BP2	IDA		Human	PMID:32245947
Molecular Function	GO:0005515	protein binding	IGF2BP2	IPI	UniProtKB:Q14103-4	Human	PMID:12674497
Molecular Function	GO:0005515	protein binding	IGF2BP2	IPI	UniProtKB:Q9NZI8	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	IGF2BP2	IPI	UniProtKB:P98179	Human	PMID:31484925
Molecular Function	GO:0005515	protein binding	IGF2BP2	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	IGF2BP2	IPI	UniProtKB:C0HLZ6	Human	PMID:34457052
Molecular Function	GO:0003723	RNA binding	IGF2BP2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	IGF2BP2	HDA		Human	PMID:22681889
Molecular Function	GO:0090079	translation regulator activity, nucleic acid binding	Igf2bp2	IMP	MGI:6281580	Mouse	PMID:25863250
Cellular Component	GO:0005737	cytoplasm	IGF2BP2	IDA		Human	PMID:15618018
Cellular Component	GO:0010494	cytoplasmic stress granule	IGF2BP2	IDA		Human	PMID:29476152
Cellular Component	GO:0005856	cytoskeleton	IGF2BP2	IDA		Human	PMID:15618018
Cellular Component	GO:0005829	cytosol	IGF2BP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	IGF2BP2	IDA		Human	PMID:15618018
Cellular Component	GO:0000932	P-body	IGF2BP2	IDA		Human	PMID:29476152
Biological Process	GO:0106106	cold-induced thermogenesis	Igf2bp2	IMP	MGI:6281580	Mouse	PMID:25863250
Biological Process	GO:0070934	CRD-mediated mRNA stabilization	IGF2BP2	IDA		Human	PMID:29476152
Biological Process	GO:0097009	energy homeostasis	Igf2bp2	IMP	MGI:6281580	Mouse	PMID:25863250
Biological Process	GO:0017148	negative regulation of translation	Igf2bp2	IMP	MGI:6281580	Mouse	PMID:25863250

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern