Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFNAR2
  • Mouse genes Ifnar2
  • Rat genes Ifnar2
  • Zfish genes crfb15
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ifnar2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019955	cytokine binding	IFNAR2	IPI	UniProtKB:P01574	Human	PMID:8798579
Molecular Function	GO:0019955	cytokine binding	IFNAR2	IPI	UniProtKB:P01574	Human	PMID:8969169
Molecular Function	GO:0005515	protein binding	IFNAR2	IPI	UniProtKB:P63244	Human	PMID:11046044
Molecular Function	GO:0005515	protein binding	IFNAR2	IPI	UniProtKB:P23458	Human	PMID:16710296
Molecular Function	GO:0005515	protein binding	IFNAR2	IPI	UniProtKB:Q9UMW8	Human	PMID:16710296
Molecular Function	GO:0005515	protein binding	IFNAR2	IPI	UniProtKB:P52630	Human	PMID:17923090
Molecular Function	GO:0005515	protein binding	IFNAR2	IPI	UniProtKB:Q00978	Human	PMID:17923090
Molecular Function	GO:0005515	protein binding	IFNAR2	IPI	UniProtKB:Q92793	Human	PMID:17923090
Molecular Function	GO:0005515	protein binding	IFNAR2	IPI	UniProtKB:P01563	Human	PMID:21854986
Molecular Function	GO:0005515	protein binding	IFNAR2	IPI	UniProtKB:P52630	Human	PMID:28165510
Molecular Function	GO:0005515	protein binding	IFNAR2	IPI	UniProtKB:Q9UMW8	Human	PMID:28165510
Molecular Function	GO:0005515	protein binding	IFNAR2	IPI	UniProtKB:P17181	Human	PMID:7665574
Molecular Function	GO:0005515	protein binding	IFNAR2	IPI	UniProtKB:P42224	Human	PMID:9121453
Molecular Function	GO:0005515	protein binding	IFNAR2	IPI	UniProtKB:P52630	Human	PMID:9121453
Molecular Function	GO:0019901	protein kinase binding	IFNAR2	IPI	UniProtKB:P23458	Human	PMID:7759950
Molecular Function	GO:0004905	type I interferon receptor activity	IFNAR2	IDA		Human	PMID:10556041
Molecular Function	GO:0004905	type I interferon receptor activity	IFNAR2	IDA		Human	PMID:21854986
Molecular Function	GO:0004905	type I interferon receptor activity	IFNAR2	IDA		Human	PMID:7665574
Molecular Function	GO:0004905	type I interferon receptor activity	IFNAR2	IDA		Human	PMID:7759950
Molecular Function	GO:0004905	type I interferon receptor activity	Ifnar2	IDA		Mouse	PMID:11154225
Molecular Function	GO:0004905	type I interferon receptor activity	Ifnar2	IDA		Mouse	PMID:9295335
Cellular Component	GO:0005615	extracellular space	Ifnar2	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Ifnar2	IDA		Mouse	PMID:11154225
Cellular Component	GO:0005886	plasma membrane	IFNAR2	IDA		Human	PMID:7759950
Biological Process	GO:0035458	cellular response to interferon-beta	IFNAR2	IDA		Human	PMID:7759950
Biological Process	GO:0051607	defense response to virus	IFNAR2	IMP		Human	PMID:26424569
Biological Process	GO:0033080	immature T cell proliferation in thymus	Ifnar2	IDA		Mouse	PMID:11154225
Biological Process	GO:0007259	receptor signaling pathway via JAK-STAT	IFNAR2	IDA		Human	PMID:10556041
Biological Process	GO:0007259	receptor signaling pathway via JAK-STAT	IFNAR2	IDA		Human	PMID:7759950
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Ifnar2	IDA		Mouse	PMID:9322767
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Ifnar2	IDA		Mouse	PMID:11154225
Biological Process	GO:0035455	response to interferon-alpha	IFNAR2	IMP		Human	PMID:26424569
Biological Process	GO:0035455	response to interferon-alpha	IFNAR2	IDA		Human	PMID:7759950
Biological Process	GO:0035456	response to interferon-beta	IFNAR2	IMP		Human	PMID:26424569
Biological Process	GO:0035456	response to interferon-beta	IFNAR2	IDA		Human	PMID:7759950
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	IFNAR2	IDA		Human	PMID:21854986
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	IFNAR2	IMP		Human	PMID:26424569
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	IFNAR2	IDA		Human	PMID:7665574

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern