Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ICAM2
  • Mouse genes Icam2
  • Rat genes Icam2
  • Zfish genes icam3,sc:d0202,si:ch211-66e2.3,si:ch211-66e2.5,si:ch211-74m13.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Icam2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005178	integrin binding	ICAM2	IPI	UniProtKB:P20701	Human	PMID:1448173
Molecular Function	GO:0005515	protein binding	Icam2	IPI	UniProtKB:P26043	Mouse	MGI:MGI:5926357|PMID:16615918
Molecular Function	GO:0005515	protein binding	Icam2	IPI	UniProtKB:P26043	Mouse	MGI:MGI:3693394|PMID:12554651
Molecular Function	GO:0005515	protein binding	Icam2	IPI	UniProtKB:P26040|UniProtKB:P26041|UniProtKB:P26043	Mouse	MGI:MGI:6115186|PMID:9472040
Molecular Function	GO:0005515	protein binding	Icam2	IPI	PR:P26043	Mouse	PMID:12068294
Cellular Component	GO:0071944	cell periphery	Icam2	IDA		Mouse	PMID:16099728
Cellular Component	GO:0032154	cleavage furrow	ICAM2	IDA		Human	PMID:19799413
Cellular Component	GO:0016020	membrane	ICAM2	HDA		Human	PMID:19946888
Cellular Component	GO:0005902	microvillus	Icam2	IDA		Mouse	MGI:MGI:6115186|PMID:9472040
Cellular Component	GO:0005886	plasma membrane	Icam2	IDA		Mouse	PMID:16099728
Cellular Component	GO:0005886	plasma membrane	Icam2	IDA		Mouse	PMID:11937524
Cellular Component	GO:0001931	uropod	Icam2	IDA		Mouse	PMID:11937524
Biological Process	GO:0060048	cardiac muscle contraction	icam3	IMP	ZFIN:ZDB-GENO-190411-12	Zfish	PMID:29777134
Biological Process	GO:0055015	ventricular cardiac muscle cell development	icam3	IMP	ZFIN:ZDB-GENO-190411-12	Zfish	PMID:29777134

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern