Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HTR1D
  • Mouse genes Htr1d
  • Rat genes Htr1d
  • Zfish genes htr1d
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Htr1d

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004993	G protein-coupled serotonin receptor activity	HTR1D	IMP		Human	PMID:1652050
Molecular Function	GO:0004993	G protein-coupled serotonin receptor activity	Htr1d	IDA		Mouse	PMID:1557407
Molecular Function	GO:0051378	serotonin binding	Htr1d	IDA		Mouse	PMID:1557407
Cellular Component	GO:0098978	glutamatergic synapse	Htr1d	EXP		Rat	PMID:8522955|RGD:155230787
Cellular Component	GO:0098978	glutamatergic synapse	Htr1d	IDA		Rat	PMID:8522955|RGD:155230787
Cellular Component	GO:0098992	neuronal dense core vesicle	Htr1d	IDA		Rat	PMID:14645495|RGD:734519
Cellular Component	GO:0005886	plasma membrane	HTR1D	IDA		Human	PMID:1652050
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	HTR1D	IMP		Human	PMID:1652050
Biological Process	GO:0014827	intestine smooth muscle contraction	HTR1D	IMP		Human	PMID:9186750
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Htr1d	EXP		Rat	PMID:8522955|RGD:155230787
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Htr1d	IDA		Rat	PMID:8522955|RGD:155230787
Biological Process	GO:0009636	response to toxic substance	Htr1d	IDA		Mouse	PMID:1557407

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern