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Gene Ontology Browser
Term Detail
GO term:serotonin receptor activity
Synonym: 5-HT receptor
Synonym: 5-hydroxytryptamine receptor
Synonym: G protein coupled serotonin receptor activity
Synonym: G-protein coupled serotonin receptor activity
Synonym: G-protein-coupled serotonin receptor activity
GO id:GO:0004993
Definition:Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-amolecular transducer activity
                        is-asignal transducer activity
                                is-asignaling receptor activity
                                        is-atransmembrane signaling receptor activity
                                                is-aG-protein coupled receptor activity
                                                        is-aG-protein coupled amine receptor activity
                                                                is-a2-phenylethylamine receptor activity
                                                                is-aadrenergic receptor activity +
                                                                is-aG-protein coupled acetylcholine receptor activity
                                                                is-ahistamine receptor activity
                                                                is-aoctopamine receptor activity
                                                                is-aserotonin receptor activity [GO:0004993] (15 genes, 28 annotations)
                                                                        is-aGi/o-coupled serotonin receptor activity
                                                                        is-aGq/11-coupled serotonin receptor activity
                                                                is-atrace-amine receptor activity +
                                                                is-atyramine receptor activity


Gene_Ontology
        is-amolecular_function
                is-areceptor activity
                        is-asignaling receptor activity
                                is-atransmembrane signaling receptor activity
                                        is-aG-protein coupled receptor activity
                                                is-aG-protein coupled amine receptor activity
                                                        is-a2-phenylethylamine receptor activity
                                                        is-aadrenergic receptor activity +
                                                        is-aG-protein coupled acetylcholine receptor activity
                                                        is-ahistamine receptor activity
                                                        is-aoctopamine receptor activity
                                                        is-aserotonin receptor activity [GO:0004993] (15 genes, 28 annotations)
                                                                is-aGi/o-coupled serotonin receptor activity
                                                                is-aGq/11-coupled serotonin receptor activity
                                                        is-atrace-amine receptor activity +
                                                        is-atyramine receptor activity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory