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Htr1d
Gene Detail
Symbol

Name
ID
Htr1d
5-hydroxytryptamine (serotonin) receptor 1D
MGI:96276
Synonyms
Gpcr14, Htr1db
Feature Type
protein coding gene
Genetic Map
Chromosome 4
68.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(12)
Sequence Map
Chr4:136423524-136444398 bp, + strand
From VEGA annotation of GRCm38

  20875 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20240  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: HTR1D
Protein SuperFamily: 5-hydroxytryptamine receptor 1
Gene Tree: Htr1d

Human
homologs
HTR1D, 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 3352
neXtProt AC: NX_P28221

Human Synonyms: 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4

Human Chr (Location): 1p36.3-p34.3; chr1:23191895-23194729 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Genomic Mutations involving Htr1d (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for disruptions in this gene display a normal phenotype.
 
Interactions
Htr1d interacts with 99 markers (Mir7-1, Mir10a, Mir26a-1, ...)
Expression
Literature Summary: (6 records)
Data Summary: Results (133)    Tissues (68)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 41
RT-PCR 92
cDNA source data(7)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: ZFIN htr1d    NEW 
Molecular
reagents
All nucleic(14) Genomic(3) cDNA(8) Primer pair(3)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000009699 (Evidence)
Ensembl Gene Model ENSMUSG00000070687 (Evidence)
Entrez Gene 15552 (Evidence)
UniGene 40573
DFCI TC1586892, TC1590657
DoTS DT.110841423, DT.50314870, DT.87048365
NIA Mouse Gene Index U004973
Consensus CDS Project CCDS18806.1
International Mouse Phenotyping Consortium Status Htr1d
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009699 VEGA Gene Model | MGI Sequence Detail 20875 C57BL/6J ±  kb
transcript OTTMUST00000022403 VEGA | MGI Sequence Detail 2426 Not Applicable 
polypeptide OTTMUSP00000036225 VEGA | MGI Sequence Detail 374 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(12) UniProt(1)
Polymorphisms
All PCR and RFLP(3) : PCR(1) RFLP(2) SNPs within 2kb(238 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000505 5-Hydroxytryptamine 1D receptor
InterPro IPR002231 5-Hydroxytryptamine receptor family
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001163 5-hydroxytryptamine receptor 1D
References
(Earliest) J:43 Maroteaux L, et al., Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):3020-4
(Latest) J:196760 Enjin A, et al., Sensorimotor function is modulated by the serotonin receptor 1d, a novel marker for gamma motor neurons. Mol Cell Neurosci. 2012 Mar;49(3):322-32
All references(49)
Other
accession IDs
MGD-MRK-11002, MGD-MRK-11004, MGD-MRK-16348, MGI:2140395, MGI:96278, MGI:99568

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory