Htr1d
Gene Detail

Symbol Name ID

Htr1d 5-hydroxytryptamine (serotonin) receptor 1D MGI:96276

Synonyms

Gpcr14, Htr1db

Feature Type

protein coding gene

Genetic Map

Chromosome 4

68.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(12)

Sequence Map

Chr4:136423524-136444398 bp, + strand From VEGA annotation of GRCm38   20875 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic; guinea pig; rabbit, European    (Mammalian Orthology)
Comparative Map (Mouse/Human Htr1d ± 2 cM)

Protein SuperFamily: 5-hydroxytryptamine receptor 1
Gene Tree: Htr1d

Human ortholog

HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled NCBI Gene ID 3352
Human Synonyms: 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4
Human Chr1:23518388-23521222 bp, - strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(4) : Targeted(4)
 

Mice homozygous for disruptions in this gene display a normal phenotype.

 

Gene Ontology (GO) classifications

All GO classifications: (24 annotations)

Process	behavior, G-protein coupled receptor signaling pathway, ...
Component	integral to membrane, integral to plasma membrane, ...
Function	G-protein coupled receptor activity, serotonin binding, ...

External Resources: FuncBase

Expression

Literature Summary: (6 records)
Data Summary: Results (133)    Tissues (68)    Images (15)
Theiler Stages: 1, 19, 23, 28

Assay Type	Results
RNA in situ	41
RT-PCR	92

cDNA source data(7)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(14) Genomic(3) cDNA(8) Primer pair(3)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000009699 (Evidence)
Ensembl Gene Model	ENSMUSG00000070687 (Evidence)
Entrez Gene	15552 (Evidence)
UniGene	40573
DFCI	TC1586892, TC1590657
DoTS	DT.110841423, DT.50314870, DT.87048365
NIA Mouse Gene Index	U004973
Consensus CDS Project	CCDS18806.1
International Mouse Knockout Project Status	Htr1d

Sequences

Length	Strain/Species
genomic	OTTMUSG00000009699	VEGA Gene Model | MGI Sequence Detail	20875	C57BL/6J
transcript	OTTMUST00000022402	VEGA | MGI Sequence Detail	2904	Not Applicable
polypeptide	OTTMUSP00000010214	VEGA | MGI Sequence Detail	374	Not Applicable

All sequences(38) RefSeq(2) UniProt(2)

Polymorphisms

All PCR and RFLP(3) : PCR(1) RFLP(2) SNPs(102 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000505	5-Hydroxytryptamine 1D receptor
InterPro	IPR002231	5-Hydroxytryptamine receptor
InterPro	IPR000276	GPCR, rhodopsin-like
InterPro	IPR017452	GPCR, rhodopsin-like, 7TM
Protein Ontology	PR:000001163	5-hydroxytryptamine receptor 1D

References

(Earliest) J:43 Maroteaux L, et al., Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):3020-4
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(48)

Other accession IDs

MGD-MRK-11002, MGD-MRK-11004, MGD-MRK-16348, MGI:2140395, MGI:96278, MGI:99568