Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HSD17B6
  • Mouse genes Hsd17b6
  • Rat genes Hsd17b6
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hsd17b6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047024	5alpha-androstane-3beta,17beta-diol dehydrogenase activity	HSD17B6	IDA		Human	PMID:11360992
Molecular Function	GO:0047024	5alpha-androstane-3beta,17beta-diol dehydrogenase activity	HSD17B6	IDA		Human	PMID:11513953
Molecular Function	GO:0047024	5alpha-androstane-3beta,17beta-diol dehydrogenase activity	Hsd17b6	IDA		Mouse	MGI:MGI:1347372|PMID:10537158
Molecular Function	GO:0047044	androstan-3-alpha,17-beta-diol dehydrogenase activity	HSD17B6	IDA		Human	PMID:11360992
Molecular Function	GO:0047044	androstan-3-alpha,17-beta-diol dehydrogenase activity	Hsd17b6	IDA		Mouse	MGI:MGI:1347372|PMID:10537158
Molecular Function	GO:0047044	androstan-3-alpha,17-beta-diol dehydrogenase activity	Hsd17b6	IDA		Rat	PMID:9188497|RGD:1299376
Molecular Function	GO:0047023	androsterone dehydrogenase activity	HSD17B6	IDA		Human	PMID:10896656
Molecular Function	GO:0047023	androsterone dehydrogenase activity	HSD17B6	IDA		Human	PMID:11360992
Molecular Function	GO:0047023	androsterone dehydrogenase activity	Hsd17b6	IDA		Mouse	MGI:MGI:1347372|PMID:10537158
Molecular Function	GO:0047023	androsterone dehydrogenase activity	Hsd17b6	IDA		Rat	PMID:9188497|RGD:1299376
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	Hsd17b6	IDA		Mouse	MGI:MGI:1347372|PMID:10537158
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	Hsd17b6	IDA		Rat	PMID:9188497|RGD:1299376
Molecular Function	GO:0004745	NAD-retinol dehydrogenase activity	HSD17B6	IDA		Human	PMID:10896656
Molecular Function	GO:0004745	NAD-retinol dehydrogenase activity	HSD17B6	IDA		Human	PMID:11360992
Molecular Function	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity	Hsd17b6	IDA		Mouse	MGI:MGI:1347372|PMID:10537158
Molecular Function	GO:0047035	testosterone dehydrogenase (NAD+) activity	Hsd17b6	IDA		Mouse	MGI:MGI:1347372|PMID:10537158
Molecular Function	GO:0047035	testosterone dehydrogenase (NAD+) activity	Hsd17b6	IDA		Rat	PMID:9188497|RGD:1299376
Biological Process	GO:0062175	brexanolone catabolic process	HSD17B6	IDA		Human	PMID:10896656
Biological Process	GO:0062175	brexanolone catabolic process	HSD17B6	IDA		Human	PMID:11360992

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern