Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HS2ST1
  • Mouse genes Hs2st1
  • Rat genes Hs2st1
  • Zfish genes hs2st1a,hs2st1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hs2st1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004394	heparan sulfate 2-O-sulfotransferase activity	Hs2st1	IMP	MGI:MGI:4439258	Mouse	PMID:19889634
Molecular Function	GO:0004394	heparan sulfate 2-O-sulfotransferase activity	Hs2st1	IDA		Mouse	PMID:15226404
Molecular Function	GO:0004394	heparan sulfate 2-O-sulfotransferase activity	Hs2st1	IMP	MGI:MGI:1934916	Mouse	PMID:11457822
Molecular Function	GO:0034483	heparan sulfate sulfotransferase activity	hs2st1a	IMP	ZFIN:ZDB-MRPHLNO-120420-2	Zfish	PMID:22357927
Molecular Function	GO:0034483	heparan sulfate sulfotransferase activity	hs2st1a	IMP	ZFIN:ZDB-MRPHLNO-120420-1	Zfish	PMID:22357927
Cellular Component	GO:0005794	Golgi apparatus	Hs2st1	IDA		Mouse	PMID:24326668
Cellular Component	GO:0005794	Golgi apparatus	Hs2st1	IDA		Mouse	PMID:11687650
Cellular Component	GO:0005794	Golgi apparatus	Hs2st1	IDA		Mouse	PMID:15226404
Cellular Component	GO:0016020	membrane	HS2ST1	HDA		Human	PMID:19946888
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	hs2st1a	IMP	ZFIN:ZDB-MRPHLNO-120420-2	Zfish	PMID:22357927
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	hs2st1a	IMP	ZFIN:ZDB-MRPHLNO-120420-1	Zfish	PMID:22357927
Biological Process	GO:0010467	gene expression	Hs2st1	IMP		Mouse	PMID:32201365
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Hs2st1	IMP	MGI:MGI:4439258	Mouse	PMID:19889634
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Hs2st1	IMP		Mouse	PMID:30377379
Biological Process	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	Hs2st1	IMP	MGI:MGI:1934916	Mouse	PMID:11457822
Biological Process	GO:0030202	heparin metabolic process	Hs2st1	IMP	MGI:MGI:1934916	Mouse	PMID:11457822
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	hs2st1a	IMP	ZFIN:ZDB-MRPHLNO-120420-2	Zfish	PMID:22357927
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	hs2st1a	IMP	ZFIN:ZDB-MRPHLNO-120420-1	Zfish	PMID:22357927
Biological Process	GO:2000047	regulation of cell-cell adhesion mediated by cadherin	hs2st1a	IMP	ZFIN:ZDB-MRPHLNO-120420-1	Zfish	PMID:22357927
Biological Process	GO:2000047	regulation of cell-cell adhesion mediated by cadherin	hs2st1a	IMP	ZFIN:ZDB-MRPHLNO-120420-2	Zfish	PMID:22357927
Biological Process	GO:0060676	ureteric bud formation	Hs2st1	IMP	MGI:MGI:1934916	Mouse	PMID:9637690

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern