Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXC11
  • Mouse genes Hoxc11
  • Rat genes Hoxc11
  • Zfish genes hoxc11a,hoxc11b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxc11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	HOXC11	IDA		Human	PMID:9582375
Molecular Function	GO:0005515	protein binding	HOXC11	IPI	UniProtKB:P42858	Human	PMID:23275563
Molecular Function	GO:0005515	protein binding	HOXC11	IPI	UniProtKB:P25786	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXC11	IPI	UniProtKB:Q15642-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXC11	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC11	IPI	UniProtKB:P01112	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC11	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXC11	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HOXC11	IDA		Human	PMID:9582375
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXC11	IDA		Human	PMID:28473536
Cellular Component	GO:0005829	cytosol	HOXC11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HOXC11	IDA		Human	GO_REF:0000052
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxc11	IGI	MGI:MGI:96203	Mouse	PMID:12869760
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxc11	IGI	MGI:MGI:96172	Mouse	PMID:12869760
Biological Process	GO:0042733	embryonic digit morphogenesis	Hoxc11	IGI	MGI:MGI:96172	Mouse	PMID:12869760
Biological Process	GO:0042733	embryonic digit morphogenesis	Hoxc11	IGI	MGI:MGI:96203	Mouse	PMID:12869760
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	Hoxc11	IGI	MGI:MGI:96203	Mouse	PMID:20978074
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	Hoxc11	IGI	MGI:MGI:96172	Mouse	PMID:20978074
Biological Process	GO:0001656	metanephros development	Hoxc11	IGI	MGI:MGI:96172	Mouse	PMID:12050119
Biological Process	GO:0001656	metanephros development	Hoxc11	IGI	MGI:MGI:96203	Mouse	PMID:12050119
Biological Process	GO:0001759	organ induction	Hoxc11	IGI	MGI:MGI:96172	Mouse	PMID:12050119
Biological Process	GO:0001759	organ induction	Hoxc11	IGI	MGI:MGI:96203	Mouse	PMID:12050119
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HOXC11	IDA		Human	PMID:9582375
Biological Process	GO:0009954	proximal/distal pattern formation	Hoxc11	IGI	MGI:MGI:96172	Mouse	PMID:12869760
Biological Process	GO:0009954	proximal/distal pattern formation	Hoxc11	IGI	MGI:MGI:96203	Mouse	PMID:12869760
Biological Process	GO:0001501	skeletal system development	Hoxc11	IGI	MGI:MGI:96203	Mouse	PMID:12869760
Biological Process	GO:0001501	skeletal system development	Hoxc11	IGI	MGI:MGI:96172	Mouse	PMID:12869760

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern