Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXC10
  • Mouse genes Hoxc10
  • Rat genes Hoxc10
  • Zfish genes hoxc10a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxc10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	HOXC10	IDA		Human	PMID:10835276
Molecular Function	GO:0005515	protein binding	HOXC10	IPI	UniProtKB:Q9UK80	Human	PMID:32296183
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HOXC10	IDA		Human	PMID:10835276
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXC10	IDA		Human	PMID:28473536
Cellular Component	GO:0016604	nuclear body	HOXC10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HOXC10	IDA		Human	GO_REF:0000052
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxc10	IGI	MGI:MGI:96171	Mouse	PMID:12869760
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxc10	IGI	MGI:MGI:96202	Mouse	PMID:12869760
Biological Process	GO:0030326	embryonic limb morphogenesis	Hoxc10	IGI	MGI:MGI:96202	Mouse	PMID:12869760
Biological Process	GO:0030326	embryonic limb morphogenesis	Hoxc10	IGI	MGI:MGI:96171	Mouse	PMID:12869760
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	HOXC10	IMP		Human	PMID:28186086
Biological Process	GO:0050905	neuromuscular process	Hoxc10	IGI	MGI:MGI:96202	Mouse	PMID:18065432
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HOXC10	IDA		Human	PMID:10835276
Biological Process	GO:0009954	proximal/distal pattern formation	Hoxc10	IGI	MGI:MGI:96202	Mouse	PMID:12869760
Biological Process	GO:0009954	proximal/distal pattern formation	Hoxc10	IGI	MGI:MGI:96171	Mouse	PMID:12869760
Biological Process	GO:0001501	skeletal system development	Hoxc10	IGI	MGI:MGI:96171	Mouse	PMID:12869760
Biological Process	GO:0001501	skeletal system development	Hoxc10	IGI	MGI:MGI:96202	Mouse	PMID:12869760
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	Hoxc10	IGI	MGI:MGI:96202	Mouse	PMID:18065432

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern