Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXB13
  • Mouse genes Hoxb13
  • Rat genes Hoxb13
  • Zfish genes hoxb13a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxb13

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	HOXB13	IDA		Human	PMID:15126340
Molecular Function	GO:0008327	methyl-CpG binding	HOXB13	IDA		Human	PMID:28473536
Molecular Function	GO:0005515	protein binding	HOXB13	IPI	UniProtKB:P17252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXB13	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXB13	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXB13	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HOXB13	IPI	UniProtKB:Q92993	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Hoxb13	IPI	PR:Q60954	Mouse	PMID:9343407
Molecular Function	GO:0043565	sequence-specific DNA binding	HOXB13	IDA		Human	PMID:23332764
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXB13	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	HOXB13	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005667	transcription regulator complex	Hoxb13	IDA		Mouse	PMID:9343407
Biological Process	GO:0001525	angiogenesis	HOXB13	IEP		Human	PMID:17972163
Biological Process	GO:0060743	epithelial cell maturation involved in prostate gland development	Hoxb13	IMP	MGI:MGI:2655242	Mouse	PMID:12668621
Biological Process	GO:0002009	morphogenesis of an epithelium	Hoxb13	IMP	MGI:MGI:2655242	Mouse	PMID:12668621
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HOXB13	IDA		Human	PMID:15126340
Biological Process	GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	Hoxb13	IGI	MGI:MGI:96205	Mouse	PMID:12620974
Biological Process	GO:0030850	prostate gland development	Hoxb13	IEP		Rat	PMID:17138648|RGD:11354895
Biological Process	GO:0040008	regulation of growth	Hoxb13	IMP	MGI:MGI:2655241	Mouse	PMID:12679105
Biological Process	GO:0033574	response to testosterone	Hoxb13	IEP		Rat	PMID:17138648|RGD:11354895
Biological Process	GO:0033574	response to testosterone	Hoxb13	IEP		Rat	PMID:17218409|RGD:2314760

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern