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Hoxb13
Gene Detail
 Symbol
Name
ID
Hoxb13
homeobox B13
MGI:107730
Feature Type protein coding gene
Genetic Map
Chromosome 11
59.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr11:96194316-96197447 bp, + strand
From VEGA annotation of GRCm38

  3132 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4640  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Hoxb13

Human
homologs
Human Homolog HOXB13, homeobox B13
NCBI Gene ID 10481
neXtProt AC  NX_Q92826
Human Synonyms  PSGD
Human Chr (Location)  17q21.2; chr17:48724763-48728749 (-)  GRCh38
Alleles
and
phenotypes
All alleles(10) : Gene trapped(3) Targeted(7)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for loss of function mutations show overgrowth in all major structures derived from the tail bud.
 
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process epithelial cell maturation involved in prostate gland development, morphogenesis of an epithelium, ...
Component nucleus, transcription factor complex
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (144)    Tissues (122)    Images (24)
Theiler Stages: 13, 14, 15, 16, 17, 19, 20, 21, 22, 23, 24, 26, 27, 28
Assay TypeResults
RNA in situ 123
RT-PCR 21
cDNA source data(31)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(41) Genomic(3) cDNA(33) Primer pair(4) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000001955 (Evidence)
Ensembl Gene ModelENSMUSG00000049604 (Evidence)
Entrez Gene15408 (Evidence)
UniGene57221
DFCITC1583557
DoTSDT.482364, DT.97380992
NIA Mouse Gene IndexU013238
Consensus CDS ProjectCCDS25291.1
International Mouse Knockout Project StatusHoxb13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001955 VEGA Gene Model | MGI Sequence Detail 3132 C57BL/6J ±  kb
transcript OTTMUST00000003919 VEGA | MGI Sequence Detail 2206 Not Applicable 
polypeptide OTTMUSP00000001896 VEGA | MGI Sequence Detail 286 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(1)
Polymorphisms RFLP(1) : SNPs within 2kb(44 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017970 Homeobox, conserved site
InterPro IPR022067 Homeobox protein Hox1A3 N-terminal
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
Protein Ontology PR:000008698 homeobox protein Hox-B13
References (Earliest) J:34769 Zeltser L, et al., Hoxb-13: a new Hox gene in a distant region of the HOXB cluster maintains colinearity. Development. 1996 Aug;122(8):2475-84
(Latest) J:190538 Simons BW, et al., Wnt signaling though beta-catenin is required for prostate lineage specification. Dev Biol. 2012 Nov 15;371(2):246-55
All references(49)
Other
accession IDs
MGD-MRK-36306

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory