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Hoxb13
Gene Detail
Symbol

Name
ID
Member of
Hoxb13
homeobox B13
MGI:107730
Hoxb cluster
Feature Type
protein coding gene
Genetic Map
Chromosome 11
59.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr11:96194316-96197447 bp, + strand
From VEGA annotation of GRCm38

  3132 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4640  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: HOXB13
Gene Tree: Hoxb13

Human
homologs
HOXB13, homeobox B13
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10481
neXtProt AC: NX_Q92826

Human Synonyms: PSGD

Human Chr (Location): 17q21.2; chr17:48724763-48728749 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(3) Targeted(9)
Genomic Mutations involving Hoxb13 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for loss of function mutations show overgrowth in all major structures derived from the tail bud.
 
Interactions
Hoxb13 interacts with 148 markers (Mir15a, Mir17, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process epithelial cell maturation involved in prostate gland development, morphogenesis of an epithelium, ...
Component nucleoplasm, nucleus, ...
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (17 records)
Data Summary: Results (143)    Tissues (123)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 122
RT-PCR 21
cDNA source data(31)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA HOXB13    NEW 
Molecular
reagents
All nucleic(41) Genomic(3) cDNA(33) Primer pair(4) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000001955 (Evidence)
Ensembl Gene Model ENSMUSG00000049604 (Evidence)
Entrez Gene 15408 (Evidence)
UniGene 57221
DFCI TC1583557
DoTS DT.97380992, DT.482364
NIA Mouse Gene Index U013238
Consensus CDS Project CCDS25291.1
International Mouse Phenotyping Consortium Status Hoxb13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001955 VEGA Gene Model | MGI Sequence Detail 3132 C57BL/6J ±  kb
transcript OTTMUST00000003919 VEGA | MGI Sequence Detail 2206 Not Applicable 
polypeptide OTTMUSP00000001896 VEGA | MGI Sequence Detail 286 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(1)
Polymorphisms
RFLP(1) : SNPs within 2kb(44 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017970 Homeobox, conserved site
InterPro IPR022067 Homeobox protein Hox1A3 N-terminal
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
Protein Ontology PR:000008698 homeobox protein Hox-B13
References
(Earliest) J:34769 Zeltser L, et al., Hoxb-13: a new Hox gene in a distant region of the HOXB cluster maintains colinearity. Development. 1996 Aug;122(8):2475-84
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(49)
Other
accession IDs
MGD-MRK-36306

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory