Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HLCS
  • Mouse genes Hlcs
  • Rat genes Hlcs
  • Zfish genes hlcs
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hlcs

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0009374	biotin binding	HLCS	IDA		Human	PMID:14613969
Molecular Function	GO:0004080	biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity	HLCS	IDA		Human	PMID:7842009
Molecular Function	GO:0004080	biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity	Hlcs	IDA		Rat	PMID:7849632|RGD:2313679
Molecular Function	GO:0018271	biotin-protein ligase activity	HLCS	IDA		Human	PMID:14613969
Molecular Function	GO:0018271	biotin-protein ligase activity	HLCS	IMP		Human	PMID:18429047
Molecular Function	GO:0018271	biotin-protein ligase activity	HLCS	IDA		Human	PMID:9630604
Molecular Function	GO:0019899	enzyme binding	HLCS	IPI	UniProtKB:P05165	Human	PMID:19157941
Molecular Function	GO:0042802	identical protein binding	Hlcs	IPI	RGD:1565360	Rat	PMID:7849632|RGD:2313679
Molecular Function	GO:0042802	identical protein binding	Hlcs	IPI	UniProtKB:D4AA38	Rat	PMID:7849632|RGD:2313679
Molecular Function	GO:0005515	protein binding	HLCS	IPI	UniProtKB:O00763	Human	PMID:20085763
Molecular Function	GO:0005515	protein binding	HLCS	IPI	UniProtKB:Q9NUX5	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	HLCS	IPI	UniProtKB:Q5T0L3	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HLCS	IPI	UniProtKB:A0JLT2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HLCS	IPI	UniProtKB:P26371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HLCS	IPI	UniProtKB:Q5T0L3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HLCS	IPI	UniProtKB:Q8N6D5	Human	PMID:32296183
Cellular Component	GO:0000785	chromatin	HLCS	IDA		Human	PMID:14613969
Cellular Component	GO:0005829	cytosol	HLCS	HDA		Human	PMID:16780588
Cellular Component	GO:0005829	cytosol	HLCS	IDA		Human	PMID:9630604
Cellular Component	GO:0005739	mitochondrion	Hlcs	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005652	nuclear lamina	HLCS	IDA		Human	PMID:14613969
Cellular Component	GO:0016363	nuclear matrix	HLCS	IDA		Human	PMID:14613969
Biological Process	GO:0043687	post-translational protein modification	HLCS	IDA		Human	PMID:14613969
Biological Process	GO:0070781	response to biotin	HLCS	IDA		Human	PMID:17904341
Biological Process	GO:0070781	response to biotin	Hlcs	IEP		Rat	PMID:16359899|RGD:2313678

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern