Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HIRA
  • Mouse genes Hira
  • Rat genes Hira
  • Zfish genes hira
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hira

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042393	histone binding	HIRA	IDA		Human	PMID:9731536
Molecular Function	GO:0005515	protein binding	HIRA	IPI	UniProtKB:Q9UMS0-2	Human	PMID:11342215
Molecular Function	GO:0005515	protein binding	HIRA	IPI	UniProtKB:Q9NVP2	Human	PMID:16980972
Molecular Function	GO:0005515	protein binding	HIRA	IPI	UniProtKB:Q9Y294	Human	PMID:16980972
Molecular Function	GO:0005515	protein binding	HIRA	IPI	UniProtKB:Q9NPG3	Human	PMID:19029251
Molecular Function	GO:0005515	protein binding	HIRA	IPI	UniProtKB:Q9Y294	Human	PMID:19029251
Molecular Function	GO:0005515	protein binding	HIRA	IPI	UniProtKB:Q9NVP2	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	HIRA	IPI	UniProtKB:Q9Y294	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	HIRA	IPI	UniProtKB:Q9Y294	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	HIRA	IPI	UniProtKB:Q9BW71	Human	PMID:9710638
Molecular Function	GO:0005515	protein binding	Hira	IPI	PR:Q9QZ23	Mouse	PMID:11342215
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	HIRA	IPI	UniProtKB:P24610	Human	PMID:9731536
Cellular Component	GO:0000785	chromatin	HIRA	IDA		Human	PMID:14718166
Cellular Component	GO:0000785	chromatin	Hira	IDA		Mouse	PMID:15922569
Cellular Component	GO:0070062	extracellular exosome	HIRA	HDA		Human	PMID:18570454
Cellular Component	GO:0005654	nucleoplasm	HIRA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	HIRA	IDA		Human	PMID:14718166
Biological Process	GO:0007369	gastrulation	Hira	IMP	MGI:MGI:2178130	Mouse	PMID:11884616
Biological Process	GO:0042692	muscle cell differentiation	Hira	IGI	MGI:MGI:1101768	Mouse	PMID:22705305
Biological Process	GO:0042692	muscle cell differentiation	Hira	IGI	MGI:MGI:1097686	Mouse	PMID:22705305
Biological Process	GO:0042692	muscle cell differentiation	Hira	IGI	MGI:MGI:3650546	Mouse	PMID:22705305
Biological Process	GO:0006334	nucleosome assembly	HIRA	IDA		Human	PMID:14718166
Biological Process	GO:0001649	osteoblast differentiation	Hira	IGI	MGI:MGI:1097686	Mouse	PMID:22705305
Biological Process	GO:0001649	osteoblast differentiation	Hira	IGI	MGI:MGI:1101768	Mouse	PMID:22705305
Biological Process	GO:0001649	osteoblast differentiation	Hira	IGI	MGI:MGI:3650546	Mouse	PMID:22705305

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern