Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HECTD1
  • Mouse genes Hectd1
  • Rat genes Hectd1
  • Zfish genes hectd1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hectd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	HECTD1	IPI	UniProtKB:Q8N6C5	Human	PMID:12421765
Molecular Function	GO:0005515	protein binding	Hectd1	IPI	PR:P07901	Mouse	PMID:22431752
Molecular Function	GO:0061630	ubiquitin protein ligase activity	HECTD1	IDA		Human	PMID:33711283
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Hectd1	IDA		Mouse	PMID:22431752
Biological Process	GO:0035904	aorta development	Hectd1	IMP		Mouse	PMID:25807483
Biological Process	GO:0001892	embryonic placenta development	Hectd1	IMP	MGI:MGI:2137552	Mouse	PMID:24855001
Biological Process	GO:0001892	embryonic placenta development	Hectd1	IMP	MGI:MGI:3706565	Mouse	PMID:24855001
Biological Process	GO:0003170	heart valve development	Hectd1	IMP		Mouse	PMID:25807483
Biological Process	GO:0001779	natural killer cell differentiation	Hectd1	IMP	MGI:MGI:2137552	Mouse	PMID:24855001
Biological Process	GO:1903077	negative regulation of protein localization to plasma membrane	Hectd1	IMP	MGI:MGI:2137552	Mouse	PMID:22431752
Biological Process	GO:1903077	negative regulation of protein localization to plasma membrane	Hectd1	IMP	MGI:MGI:3706565	Mouse	PMID:22431752
Biological Process	GO:0001843	neural tube closure	Hectd1	IMP		Mouse	MGI:MGI:3714713|PMID:17442300
Biological Process	GO:0001843	neural tube closure	Hectd1	IMP	MGI:MGI:2137552	Mouse	PMID:15755804
Biological Process	GO:0001843	neural tube closure	Hectd1	IMP	MGI:MGI:2137552	Mouse	PMID:9636176
Biological Process	GO:0051865	protein autoubiquitination	Hectd1	IMP		Mouse	PMID:22431752
Biological Process	GO:0070534	protein K63-linked ubiquitination	Hectd1	IMP	MGI:MGI:2137552	Mouse	PMID:22431752
Biological Process	GO:0070534	protein K63-linked ubiquitination	Hectd1	IDA		Mouse	PMID:22431752
Biological Process	GO:0070534	protein K63-linked ubiquitination	Hectd1	IMP		Mouse	PMID:22431752
Biological Process	GO:0070534	protein K63-linked ubiquitination	Hectd1	IMP	MGI:MGI:3706565	Mouse	PMID:22431752
Biological Process	GO:0072659	protein localization to plasma membrane	Hectd1	IMP	MGI:MGI:2137552	Mouse	PMID:22431752
Biological Process	GO:0072659	protein localization to plasma membrane	Hectd1	IMP	MGI:MGI:3706565	Mouse	PMID:22431752
Biological Process	GO:0060708	spongiotrophoblast differentiation	Hectd1	IMP	MGI:MGI:2137552	Mouse	PMID:24855001
Biological Process	GO:0060707	trophoblast giant cell differentiation	Hectd1	IMP	MGI:MGI:2137552	Mouse	PMID:24855001
Biological Process	GO:0003281	ventricular septum development	Hectd1	IMP		Mouse	PMID:25807483

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern