Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HAS3
  • Mouse genes Has3
  • Rat genes Has3
  • Zfish genes has3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Has3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050501	hyaluronan synthase activity	HAS3	IDA		Human	PMID:16900089
Molecular Function	GO:0050501	hyaluronan synthase activity	HAS3	IDA		Human	PMID:23303191
Molecular Function	GO:0050501	hyaluronan synthase activity	Has3	IDA		Mouse	PMID:10455188
Molecular Function	GO:0050501	hyaluronan synthase activity	Has3	IDA		Mouse	PMID:9060470
Molecular Function	GO:0042802	identical protein binding	HAS3	IPI	UniProtKB:O00219	Human	PMID:25795779
Molecular Function	GO:0005515	protein binding	HAS3	IPI	UniProtKB:Q92819	Human	PMID:20507985
Molecular Function	GO:0005515	protein binding	HAS3	IPI	UniProtKB:Q92819	Human	PMID:25795779
Molecular Function	GO:0005515	protein binding	HAS3	IPI	UniProtKB:Q92839	Human	PMID:25795779
Cellular Component	GO:0005737	cytoplasm	Has3	IDA		Mouse	MGI:MGI:5619725|PMID:24057227
Cellular Component	GO:0005794	Golgi apparatus	HAS3	IDA		Human	PMID:25795779
Cellular Component	GO:0036117	hyaluranon cable	HAS3	IDA		Human	PMID:16900089
Cellular Component	GO:0005634	nucleus	Has3	IDA		Mouse	MGI:MGI:5619725|PMID:24057227
Cellular Component	GO:0005886	plasma membrane	HAS3	IDA		Human	PMID:25795779
Cellular Component	GO:0005886	plasma membrane	HAS3	IDA		Human	PMID:26883802
Cellular Component	GO:0005886	plasma membrane	Has3	IDA		Mouse	PMID:10455188
Biological Process	GO:0085029	extracellular matrix assembly	Has3	IDA		Mouse	MGI:MGI:5508296|PMID:10455188
Biological Process	GO:0045226	extracellular polysaccharide biosynthetic process	Has3	IDA		Mouse	MGI:MGI:5508296|PMID:10455188
Biological Process	GO:0030213	hyaluronan biosynthetic process	HAS3	IDA		Human	PMID:16900089
Biological Process	GO:0030213	hyaluronan biosynthetic process	Has3	IDA		Mouse	PMID:10455188
Biological Process	GO:0030213	hyaluronan biosynthetic process	Has3	IDA		Mouse	PMID:9060470
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	HAS3	IDA		Human	PMID:16900089
Biological Process	GO:1900106	positive regulation of hyaluranon cable assembly	HAS3	IDA		Human	PMID:16900089

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern