Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HAS1
  • Mouse genes Has1
  • Rat genes Has1
  • Zfish genes has1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Has1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050501	hyaluronan synthase activity	Has1	IDA		Mouse	PMID:10455188
Molecular Function	GO:0050501	hyaluronan synthase activity	Has1	IDA		Mouse	PMID:8626618
Molecular Function	GO:0050501	hyaluronan synthase activity	Has1	IDA		Mouse	PMID:10617644
Molecular Function	GO:0042802	identical protein binding	HAS1	IPI	UniProtKB:Q92839	Human	PMID:25795779
Molecular Function	GO:0005515	protein binding	HAS1	IPI	UniProtKB:O00219	Human	PMID:25795779
Molecular Function	GO:0005515	protein binding	HAS1	IPI	UniProtKB:Q92819	Human	PMID:25795779
Cellular Component	GO:0005737	cytoplasm	Has1	IDA		Mouse	MGI:MGI:5619725|PMID:24057227
Cellular Component	GO:0005794	Golgi apparatus	HAS1	IDA		Human	PMID:25795779
Cellular Component	GO:0016020	membrane	Has1	IDA		Mouse	PMID:10617644
Cellular Component	GO:0005886	plasma membrane	HAS1	IDA		Human	PMID:25795779
Cellular Component	GO:0005886	plasma membrane	Has1	IDA		Mouse	PMID:8626618
Cellular Component	GO:0005886	plasma membrane	Has1	IDA		Mouse	PMID:10455188
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	HAS1	IDA		Human	PMID:17324121
Biological Process	GO:0044849	estrous cycle	Has1	IEP		Rat	PMID:24218629|RGD:9588635
Biological Process	GO:0085029	extracellular matrix assembly	Has1	IDA		Mouse	MGI:MGI:5508296|PMID:10455188
Biological Process	GO:0045226	extracellular polysaccharide biosynthetic process	Has1	IDA		Mouse	MGI:MGI:5508296|PMID:10455188
Biological Process	GO:0030213	hyaluronan biosynthetic process	Has1	IMP		Mouse	PMID:8626618
Biological Process	GO:0030213	hyaluronan biosynthetic process	Has1	IDA		Mouse	PMID:10455188
Biological Process	GO:0030213	hyaluronan biosynthetic process	Has1	IDA		Mouse	PMID:10617644
Biological Process	GO:0010764	negative regulation of fibroblast migration	HAS1	IMP		Human	PMID:19577615

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern